STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HSD17B2Estradiol 17-beta-dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (385 aa)    
Predicted Functional Partners:
HSD17B1
Estradiol 17-beta-dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
 
0.975
L8Y9K4_TUPCH
Steroid 17-alpha-hydroxylase/17,20 lyase; Belongs to the cytochrome P450 family.
   
 
 0.933
SRD5A2
3-oxo-5-alpha-steroid 4-dehydrogenase 2.
   
 
 0.924
L8Y5I1_TUPCH
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase.
   
 
 0.923
HSD17B12
Estradiol 17-beta-dehydrogenase 12.
     
 0.923
L9JCM9_TUPCH
Prostaglandin-E(2) 9-reductase.
   
 
 0.917
L9KL08_TUPCH
Cytochrome P450 11B2, mitochondrial; Belongs to the cytochrome P450 family.
   
 
 0.917
L9L9T5_TUPCH
Aldo-keto reductase family 1 member C1 like protein.
   
 
 0.917
L9KQ01_TUPCH
Cytochrome P450 3A12.
   
 
 0.912
L9KND1_TUPCH
Cytochrome P450 1B1; Belongs to the cytochrome P450 family.
   
 
 0.911
Your Current Organism:
Tupaia chinensis
NCBI taxonomy Id: 246437
Other names: Chinese tree shrew, T. chinensis, Tupaia belangeri chinensis
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.