STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
L9KS40_TUPCHGuanine nucleotide exchange factor VAV3. (1064 aa)    
Predicted Functional Partners:
GRB2
Growth factor receptor-bound protein 2.
    
0.967
L8YAA3_TUPCH
Tyrosine-protein kinase SYK.
   
 0.953
L9KYJ2_TUPCH
Lymphocyte cytosolic protein 2.
   
 0.928
ZAP70
Tyrosine-protein kinase.
   
 0.848
NFATC2IP
B-lymphocyte antigen CD19.
   
 0.804
RAC2
Ras-related C3 botulinum toxin substrate 2.
   
 0.797
L9L8A7_TUPCH
Ras-related C3 botulinum toxin substrate 1.
   
 0.797
GRAP2
GRB2-related adapter protein 2.
    
0.779
NCK1
Cytoplasmic protein NCK1.
    
0.766
CBL
E3 ubiquitin-protein ligase CBL.
    
 0.762
Your Current Organism:
Tupaia chinensis
NCBI taxonomy Id: 246437
Other names: Chinese tree shrew, T. chinensis, Tupaia belangeri chinensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.