STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AGO1Protein argonaute-1; Belongs to the argonaute family. (850 aa)    
Predicted Functional Partners:
L8YAM4_TUPCH
Endoribonuclease Dicer.
   
 0.921
L9KKH6_TUPCH
Protein argonaute-2.
  
 
0.872
L9KL27_TUPCH
Protein argonaute-2.
  
 
0.872
L9KTE8_TUPCH
Trinucleotide repeat-containing 6B protein.
    
 0.856
TNRC6C
Trinucleotide repeat-containing 6C protein.
    
 0.855
L9KUJ0_TUPCH
Ribonuclease 3.
   
 0.836
TARBP2
RISC-loading complex subunit TARBP2; Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from [...]
    
 0.830
L9KPW4_TUPCH
Putative ATP-dependent RNA helicase DDX6; Belongs to the DEAD box helicase family.
   
 
 0.753
L9KT83_TUPCH
Protein argonaute-3; Belongs to the argonaute family.
  
 
0.720
L9L0L4_TUPCH
Fragile X mental retardation syndrome-related protein 1.
    
 
 0.716
Your Current Organism:
Tupaia chinensis
NCBI taxonomy Id: 246437
Other names: Chinese tree shrew, T. chinensis, Tupaia belangeri chinensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.