STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
L9KZM5_TUPCHE3 ubiquitin-protein ligase UBR5. (2032 aa)    
Predicted Functional Partners:
UBR5
E3 ubiquitin-protein ligase UBR5.
 
     0.944
TRIP12
Putative E3 ubiquitin-protein ligase TRIP12.
   
  
0.927
L9J8R3_TUPCH
Eukaryotic translation initiation factor 4 gamma 1.
   
 
 0.804
UBA52
Ubiquitin-60S ribosomal protein L40.
    
   0.775
L9KKR5_TUPCH
Ubiquitin carboxyl-terminal hydrolase 34; Belongs to the peptidase C19 family.
   
  
 0.642
ARFGEF1
Brefeldin A-inhibited guanine nucleotide-exchange protein 1.
   
    0.610
L9JGG4_TUPCH
E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
   
  
 0.583
L9JSH8_TUPCH
Nipped-B protein.
   
  
 0.555
L8YA29_TUPCH
Eukaryotic translation initiation factor 4 gamma 2.
   
   0.551
L9JLR9_TUPCH
Mitotic checkpoint serine/threonine-protein kinase BUB1.
    
   0.533
Your Current Organism:
Tupaia chinensis
NCBI taxonomy Id: 246437
Other names: Chinese tree shrew, T. chinensis, Tupaia belangeri chinensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.