| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KEZ53631.1 | KEZ54189.1 | GS18_0201215 | GS18_0204490 | uroporphyrinogen-III synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | uroporphyrin-III methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.891 |
| KEZ53631.1 | KEZ54190.1 | GS18_0201215 | GS18_0204495 | uroporphyrinogen-III synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.528 |
| KEZ53631.1 | hemE | GS18_0201215 | GS18_0221475 | uroporphyrinogen-III synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.887 |
| KEZ54186.1 | KEZ54189.1 | GS18_0204475 | GS18_0204490 | Sulfate permease; Derived by automated computational analysis using gene prediction method: Protein Homology. | uroporphyrin-III methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.655 |
| KEZ54186.1 | KEZ54190.1 | GS18_0204475 | GS18_0204495 | Sulfate permease; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.610 |
| KEZ54186.1 | cysC | GS18_0204475 | GS18_0204485 | Sulfate permease; Derived by automated computational analysis using gene prediction method: Protein Homology. | Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. | 0.751 |
| KEZ54186.1 | cysH | GS18_0204475 | GS18_0204470 | Sulfate permease; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. | 0.879 |
| KEZ54186.1 | sat | GS18_0204475 | GS18_0204480 | Sulfate permease; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP sulfurylase; ATPS; converts ATP and sulfate to 5'phosphosulfate and pyrophosphate; in some organisms this enzyme is involved in the incorporation of inorganic sulfate while in others it is involved in the production of ATP in the reverse direction; the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.798 |
| KEZ54189.1 | KEZ53631.1 | GS18_0204490 | GS18_0201215 | uroporphyrin-III methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology. | uroporphyrinogen-III synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.891 |
| KEZ54189.1 | KEZ54186.1 | GS18_0204490 | GS18_0204475 | uroporphyrin-III methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology. | Sulfate permease; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.655 |
| KEZ54189.1 | KEZ54190.1 | GS18_0204490 | GS18_0204495 | uroporphyrin-III methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.995 |
| KEZ54189.1 | KEZ54393.1 | GS18_0204490 | GS18_0205610 | uroporphyrin-III methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cobinamide adenolsyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.631 |
| KEZ54189.1 | cobQ | GS18_0204490 | GS18_0205605 | uroporphyrin-III methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cobalamin biosynthesis protein CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.689 |
| KEZ54189.1 | cysC | GS18_0204490 | GS18_0204485 | uroporphyrin-III methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology. | Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. | 0.915 |
| KEZ54189.1 | cysH | GS18_0204490 | GS18_0204470 | uroporphyrin-III methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. | 0.956 |
| KEZ54189.1 | cysI | GS18_0204490 | GS18_0208280 | uroporphyrin-III methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology. | Sulfite reductase; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 0.921 |
| KEZ54189.1 | hemE | GS18_0204490 | GS18_0221475 | uroporphyrin-III methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.891 |
| KEZ54189.1 | sat | GS18_0204490 | GS18_0204480 | uroporphyrin-III methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP sulfurylase; ATPS; converts ATP and sulfate to 5'phosphosulfate and pyrophosphate; in some organisms this enzyme is involved in the incorporation of inorganic sulfate while in others it is involved in the production of ATP in the reverse direction; the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.907 |
| KEZ54190.1 | KEZ53631.1 | GS18_0204495 | GS18_0201215 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | uroporphyrinogen-III synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.528 |
| KEZ54190.1 | KEZ54186.1 | GS18_0204495 | GS18_0204475 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Sulfate permease; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.610 |
