Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
spoIIABAnti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. (146 aa)    
Predicted Functional Partners:
KEZ51495.1
Anti-sigma F factor antagonist; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the anti-sigma-factor antagonist family.
 
 
 0.999
KEZ51493.1
Sporulation sigma factor SigF; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
 
 0.995
KEZ54161.1
Peptidase; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR.
  
  
 0.948
KEZ49064.1
Stage II sporulation protein R; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.902
KEZ51486.1
Stage V sporulation protein AF; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.890
KEZ51490.1
Stage V sporulation protein AC; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.884
KEZ51752.1
Stage IV sporulation protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.883
KEZ54163.1
Sporulation sigma factor SigG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
  
 0.876
KEZ49702.1
Stage II sporulation protein E; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.876
KEZ51489.1
Stage V sporulation protein AD; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.875
Your Current Organism:
Bacillus indicus
NCBI taxonomy Id: 246786
Other names: B. indicus, Bacillus cibi, Bacillus cibi Yoon et al. 2005, Bacillus indicus Suresh et al. 2004 emend. Stropko et al. 2014, Bacillus sp. KU12, Bacillus sp. KU14, DSM 15820, DSM 16189 [[Bacillus cibi]], JCM 12168, KCTC 3880 [[Bacillus cibi]], LMG 22858, LMG:22858, MTCC 4374, strain JG-30 [[Bacillus cibi]], strain Sd/3
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