| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KEZ51577.1 | KEZ51747.1 | GS18_0210600 | GS18_0211550 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 0.871 |
| KEZ51577.1 | cpdB | GS18_0210600 | GS18_0219415 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2', 3'-cyclic nucleotide 2'-phosphodiesterase; In Escherichia coli this is a periplasmic enzyme while in gram positive organisms it may be anchored at the cell surface; this protein appears to consist of a dimer fusion; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.840 |
| KEZ51577.1 | deoA | GS18_0210600 | GS18_0210135 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thymidine phosphorylase; Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.960 |
| KEZ51577.1 | tdk | GS18_0210600 | GS18_0216765 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thymidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.934 |
| KEZ51577.1 | udk | GS18_0210600 | GS18_0211845 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Uridine kinase; Functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.919 |
| KEZ51747.1 | KEZ51577.1 | GS18_0211550 | GS18_0210600 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.871 |
| KEZ51747.1 | KEZ51778.1 | GS18_0211550 | GS18_0211705 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Competence protein ComE; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.640 |
| KEZ51747.1 | cpdB | GS18_0211550 | GS18_0219415 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 2', 3'-cyclic nucleotide 2'-phosphodiesterase; In Escherichia coli this is a periplasmic enzyme while in gram positive organisms it may be anchored at the cell surface; this protein appears to consist of a dimer fusion; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.862 |
| KEZ51747.1 | deoA | GS18_0211550 | GS18_0210135 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Thymidine phosphorylase; Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.993 |
| KEZ51747.1 | tdk | GS18_0211550 | GS18_0216765 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Thymidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.935 |
| KEZ51747.1 | udk | GS18_0211550 | GS18_0211845 | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | Uridine kinase; Functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.919 |
| KEZ51778.1 | KEZ51747.1 | GS18_0211705 | GS18_0211550 | Competence protein ComE; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 0.640 |
| KEZ51778.1 | cpdB | GS18_0211705 | GS18_0219415 | Competence protein ComE; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2', 3'-cyclic nucleotide 2'-phosphodiesterase; In Escherichia coli this is a periplasmic enzyme while in gram positive organisms it may be anchored at the cell surface; this protein appears to consist of a dimer fusion; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.841 |
| KEZ51778.1 | tdk | GS18_0211705 | GS18_0216765 | Competence protein ComE; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thymidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.874 |
| KEZ51778.1 | thyA | GS18_0211705 | GS18_0208930 | Competence protein ComE; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.879 |
| KEZ51778.1 | tmk | GS18_0211705 | GS18_0214645 | Competence protein ComE; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.863 |
| KEZ51861.1 | KEZ53991.1 | GS18_0212185 | GS18_0203420 | Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.854 |
| KEZ51861.1 | cpdB | GS18_0212185 | GS18_0219415 | Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | 2', 3'-cyclic nucleotide 2'-phosphodiesterase; In Escherichia coli this is a periplasmic enzyme while in gram positive organisms it may be anchored at the cell surface; this protein appears to consist of a dimer fusion; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.838 |
| KEZ51861.1 | tdk | GS18_0212185 | GS18_0216765 | Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Thymidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.838 |
| KEZ51861.1 | thyA | GS18_0212185 | GS18_0208930 | Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.838 |
