Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
topB_4DNA topoisomerase 3. (695 aa)    
Predicted Functional Partners:
ALJ60304.1
Hypothetical protein.
 
 
 
 0.831
ALJ60302.1
Hypothetical protein.
 
     0.798
recQ_4
ATP-dependent DNA helicase RecQ.
  
 0.791
recQ_5
ATP-dependent DNA helicase RecQ.
  
 0.791
uvrD2
ATP-dependent DNA helicase UvrD2.
 
 0.757
ALJ60301.1
N-6 DNA Methylase.
 
   
 0.726
nifJ
Pyruvate-flavodoxin oxidoreductase.
  
   0.678
ALJ60306.1
Helix-turn-helix domain protein.
 
     0.629
ALJ57441.1
Helix-turn-helix domain protein.
 
     0.481
ALJ60305.1
Hypothetical protein.
       0.478
Your Current Organism:
Bacteroides cellulosilyticus
NCBI taxonomy Id: 246787
Other names: B. cellulosilyticus, Bacteroides cellulosilyticus Robert et al. 2007 emend. Hahnke et al. 2016, CCUG 44979, DSM 14838, JCM 15632, strain CRE21
Server load: low (16%) [HD]