nfo protein (Bacteroides cellulosilyticus) - STRING interaction network

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nfo

Endonuclease 4; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. (279 aa)

Predicted Functional Partners:

exoA

0.814

ung

0.775

nth

0.674

ALJ58631.1

0.674

hisB

0.668

ALJ61786.1

0.540

polA

0.492

ALJ61788.1

0.476

ALJ62575.1

0.449

sodB

0.431

Your Current Organism:

Bacteroides cellulosilyticus

NCBI taxonomy Id: 246787
Other names: B. cellulosilyticus, Bacteroides cellulosilyticus Robert et al. 2007 emend. Hahnke et al. 2016, CCUG 44979, DSM 14838, JCM 15632, strain CRE21

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALJ58631.1	exoA	BcellWH2_01370	BcellWH2_00521	Hypothetical protein.	Exodeoxyribonuclease.	0.776
ALJ58631.1	nfo	BcellWH2_01370	BcellWH2_04572	Hypothetical protein.	Endonuclease 4; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.	0.674
ALJ58631.1	polA	BcellWH2_01370	BcellWH2_02682	Hypothetical protein.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.526
ALJ61786.1	nfo	BcellWH2_04571	BcellWH2_04572	Hypothetical protein.	Endonuclease 4; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.	0.540
ALJ61788.1	nfo	BcellWH2_04573	BcellWH2_04572	Transposase, Mutator family.	Endonuclease 4; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.	0.476
ALJ62575.1	nfo	BcellWH2_05375	BcellWH2_04572	Putative GTP cyclohydrolase 1 type 2; Belongs to the GTP cyclohydrolase I type 2/NIF3 family.	Endonuclease 4; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.	0.449
exoA	ALJ58631.1	BcellWH2_00521	BcellWH2_01370	Exodeoxyribonuclease.	Hypothetical protein.	0.776
exoA	hisB	BcellWH2_00521	BcellWH2_01072	Exodeoxyribonuclease.	Histidine biosynthesis bifunctional protein HisB; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.	0.716
exoA	nfo	BcellWH2_00521	BcellWH2_04572	Exodeoxyribonuclease.	Endonuclease 4; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.	0.814
exoA	nth	BcellWH2_00521	BcellWH2_01274	Exodeoxyribonuclease.	Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.	0.974
exoA	polA	BcellWH2_00521	BcellWH2_02682	Exodeoxyribonuclease.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.748
exoA	ung	BcellWH2_00521	BcellWH2_01601	Exodeoxyribonuclease.	Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.	0.722
hisB	exoA	BcellWH2_01072	BcellWH2_00521	Histidine biosynthesis bifunctional protein HisB; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.	Exodeoxyribonuclease.	0.716
hisB	nfo	BcellWH2_01072	BcellWH2_04572	Histidine biosynthesis bifunctional protein HisB; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.	Endonuclease 4; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.	0.668
nfo	ALJ58631.1	BcellWH2_04572	BcellWH2_01370	Endonuclease 4; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.	Hypothetical protein.	0.674
nfo	ALJ61786.1	BcellWH2_04572	BcellWH2_04571	Endonuclease 4; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.	Hypothetical protein.	0.540
nfo	ALJ61788.1	BcellWH2_04572	BcellWH2_04573	Endonuclease 4; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.	Transposase, Mutator family.	0.476
nfo	ALJ62575.1	BcellWH2_04572	BcellWH2_05375	Endonuclease 4; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.	Putative GTP cyclohydrolase 1 type 2; Belongs to the GTP cyclohydrolase I type 2/NIF3 family.	0.449
nfo	exoA	BcellWH2_04572	BcellWH2_00521	Endonuclease 4; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.	Exodeoxyribonuclease.	0.814
nfo	hisB	BcellWH2_04572	BcellWH2_01072	Endonuclease 4; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.	Histidine biosynthesis bifunctional protein HisB; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.	0.668

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