node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ALJ61864.1 | eam | BcellWH2_04650 | BcellWH2_04542 | Carboxynorspermidine synthase. | Glutamate 2,3-aminomutase. | 0.900 |
ALJ61864.1 | lysA | BcellWH2_04650 | BcellWH2_05056 | Carboxynorspermidine synthase. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.920 |
dapA | dapF | BcellWH2_05361 | BcellWH2_05259 | 4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.630 |
dapA | lysA | BcellWH2_05361 | BcellWH2_05056 | 4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.740 |
dapA | lysC_2 | BcellWH2_05361 | BcellWH2_05055 | 4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | Lysine-sensitive aspartokinase 3; Belongs to the aspartokinase family. | 0.447 |
dapF | dapA | BcellWH2_05259 | BcellWH2_05361 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.630 |
dapF | ddh | BcellWH2_05259 | BcellWH2_01403 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Meso-diaminopimelate D-dehydrogenase; Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate. | 0.912 |
dapF | lysA | BcellWH2_05259 | BcellWH2_05056 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.939 |
dapF | murE | BcellWH2_05259 | BcellWH2_02378 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--LD- lysine ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.938 |
ddh | dapF | BcellWH2_01403 | BcellWH2_05259 | Meso-diaminopimelate D-dehydrogenase; Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.912 |
ddh | lysA | BcellWH2_01403 | BcellWH2_05056 | Meso-diaminopimelate D-dehydrogenase; Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.912 |
ddh | murE | BcellWH2_01403 | BcellWH2_02378 | Meso-diaminopimelate D-dehydrogenase; Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--LD- lysine ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.900 |
eam | ALJ61864.1 | BcellWH2_04542 | BcellWH2_04650 | Glutamate 2,3-aminomutase. | Carboxynorspermidine synthase. | 0.900 |
eam | lysA | BcellWH2_04542 | BcellWH2_05056 | Glutamate 2,3-aminomutase. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.808 |
ftsE | hisE | BcellWH2_05054 | BcellWH2_05053 | Cell division ATP-binding protein FtsE. | Phosphoribosyl-ATP pyrophosphatase; In the N-terminal section; belongs to the PRA-CH family. | 0.778 |
ftsE | hisF | BcellWH2_05054 | BcellWH2_05052 | Cell division ATP-binding protein FtsE. | Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.666 |
ftsE | lysA | BcellWH2_05054 | BcellWH2_05056 | Cell division ATP-binding protein FtsE. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.664 |
ftsE | lysC_2 | BcellWH2_05054 | BcellWH2_05055 | Cell division ATP-binding protein FtsE. | Lysine-sensitive aspartokinase 3; Belongs to the aspartokinase family. | 0.807 |
hisE | ftsE | BcellWH2_05053 | BcellWH2_05054 | Phosphoribosyl-ATP pyrophosphatase; In the N-terminal section; belongs to the PRA-CH family. | Cell division ATP-binding protein FtsE. | 0.778 |
hisE | hisF | BcellWH2_05053 | BcellWH2_05052 | Phosphoribosyl-ATP pyrophosphatase; In the N-terminal section; belongs to the PRA-CH family. | Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.999 |