STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
preANAD-dependent dihydropyrimidine dehydrogenase subunit PreA; Catalyzes the conversion of dihydroorotate to orotate. (325 aa)    
Predicted Functional Partners:
pyrK
Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).
 
 0.985
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
 
 0.980
pyrC
Dihydroorotase.
  
 0.975
pyrD
Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate.
  
  
 
0.909
asrB
Anaerobic sulfite reductase subunit B.
  
 
 0.829
ALJ62286.1
Hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
     
 0.810
nifJ
Pyruvate-flavodoxin oxidoreductase.
 
 
 
 0.785
pheT
Phenylalanine--tRNA ligase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
  
  
 0.777
pyrB
Aspartate carbamoyltransferase catalytic chain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
  
  
 0.754
pyrF
Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily.
  
  
 0.754
Your Current Organism:
Bacteroides cellulosilyticus
NCBI taxonomy Id: 246787
Other names: B. cellulosilyticus, Bacteroides cellulosilyticus Robert et al. 2007 emend. Hahnke et al. 2016, CCUG 44979, DSM 14838, JCM 15632, strain CRE21
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