STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TAM4_281Integral membrane protein. (173 aa)    
Predicted Functional Partners:
adkA
Adenylate kinase archaeal type; Belongs to the archaeal adenylate kinase family.
 
    0.882
rpl34e
LSU ribosomal protein L34e; Belongs to the eukaryotic ribosomal protein eL34 family.
 
     0.737
cmk
Cytidylate kinase.
 
     0.724
secY
Preprotein translocase secY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
 
    0.708
rpl15
LSU ribosomal protein L27Ae (L15p); Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
 
    0.677
rpl14e
LSU ribosomal protein L14e; Belongs to the eukaryotic ribosomal protein eL14 family.
       0.672
rpl32e
LSU ribosomal protein L32e; Belongs to the eukaryotic ribosomal protein eL32 family.
 
    0.646
rps5
SSU ribosomal protein S2e (S5p); With S4 and S12 plays an important role in translational accuracy.
  
    0.617
TAM4_1166
Conserved hypothetical protein.
 
     0.614
rps3
SSU ribosomal protein S3e (S3p); Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family.
 
    0.583
Your Current Organism:
Thermococcus sp. AM4
NCBI taxonomy Id: 246969
Other names: T. sp. AM4
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.