Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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co-expression
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[Homology]
Score
TAM4_293tRNA(U54)-2-thioribothymidine synthetase. (306 aa)    
Predicted Functional Partners:
TAM4_1286
ATPase, PP-loop superfamily.
     
  0.857
thiI
Thiamine biosynthesis protein ThiI-like protein; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
 
 
 0.721
TAM4_1529
Thiamine biosynthesis protein ThiI.
  
 
 0.682
TAM4_755
tRNA (adenine57/58-N1)-methyltransferase.
 
  
 0.649
TAM4_1399
Oxidoreductase.
       0.647
carS
Integral membrane protein; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids.
       0.565
TAM4_358
tRNA N6-threonylcarbamoyladenosine 2-methylthiotransferase.
  
  
 0.528
rps28e
SSU ribosomal protein S28e; Belongs to the eukaryotic ribosomal protein eS28 family.
  
  
  0.514
TAM4_1214
Molybdopterin converting factor subunit 2.
    
 0.481
Your Current Organism:
Thermococcus sp. AM4
NCBI taxonomy Id: 246969
Other names: T. sp. AM4
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