STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cmkCytidylate kinase. (197 aa)    
Predicted Functional Partners:
rpl34e
LSU ribosomal protein L34e; Belongs to the eukaryotic ribosomal protein eL34 family.
  
    0.987
rpl14e
LSU ribosomal protein L14e; Belongs to the eukaryotic ribosomal protein eL14 family.
  
    0.985
truB
tRNA pseudouridine 55 synthase; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
      0.973
rpl24
LSU ribosomal protein L26e (L24p); Located at the polypeptide exit tunnel on the outside of the subunit.
  
    0.960
rpl14
LSU ribosomal protein L23e (L14p); Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
  
    0.958
rps4e
SSU ribosomal protein S4e; Belongs to the eukaryotic ribosomal protein eS4 family.
  
    0.951
rpl5
LSU ribosomal protein L11e (L5p); This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
  
    0.949
rpl4
LSU ribosomal protein L1e (L4p); Forms part of the polypeptide exit tunnel.
  
    0.948
rpl22
LSU ribosomal protein L17e (L22p); The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
  
    0.947
rpl32e
LSU ribosomal protein L32e; Belongs to the eukaryotic ribosomal protein eL32 family.
 
    0.946
Your Current Organism:
Thermococcus sp. AM4
NCBI taxonomy Id: 246969
Other names: T. sp. AM4
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