Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TAM4_41Hydrolase, HAD superfamily. (233 aa)    
Predicted Functional Partners:
TAM4_185
Phosphatidate cytidylyltransferase.
       0.897
TAM4_117
Conserved hypothetical protein.
       0.834
TAM4_302
NapA-4 Na+/H+ antiporter.
       0.834
mfnA
L-tyrosine decarboxylase; Catalyzes the decarboxylation of L-aspartate to produce beta- alanine; Belongs to the group II decarboxylase family. MfnA subfamily.
  
    0.822
TAM4_15
Alpha-amylase.
       0.821
TAM4_1690
Hydrolase, HAD superfamily.
  
     0.499
TAM4_176
Archaeal ATPase, fused to C-terminal DUF234 domain protein.
       0.466
TAM4_1549
Phosphoglycolate phosphatase.
 
   
 0.462
Your Current Organism:
Thermococcus sp. AM4
NCBI taxonomy Id: 246969
Other names: T. sp. AM4
Server load: low (18%) [HD]