TAM4_577 protein (Thermococcus sp. AM4) - STRING interaction network

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Score

TAM4_577

Predicted RNA-binding protein. (206 aa)

Predicted Functional Partners:

rpl21e

0.937

rsmA

0.910

TAM4_823

0.884

pus10

0.808

dnaG

0.739

nac

0.674

spt4

0.672

cca

0.665

polC

0.656

eif5a

0.652

Your Current Organism:

Thermococcus sp. AM4

NCBI taxonomy Id: 246969
Other names: T. sp. AM4

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
TAM4_577	TAM4_823	TAM4_577	TAM4_823	Predicted RNA-binding protein.	DNA-directed RNA polymerase subunit F.	0.884
TAM4_577	cca	TAM4_577	TAM4_1025	Predicted RNA-binding protein.	tRNA nucleotidyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.	0.665
TAM4_577	dnaG	TAM4_577	TAM4_1737	Predicted RNA-binding protein.	DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.	0.739
TAM4_577	eif5a	TAM4_577	TAM4_780	Predicted RNA-binding protein.	Eukaryotic translation initiation factor eIF-5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.	0.652
TAM4_577	nac	TAM4_577	TAM4_2454	Predicted RNA-binding protein.	Nascent polypeptide-associated complex protein; Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family.	0.674
TAM4_577	polC	TAM4_577	TAM4_1407	Predicted RNA-binding protein.	Archaeal DNA polymerase II large subunit; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.	0.656
TAM4_577	pus10	TAM4_577	TAM4_636	Predicted RNA-binding protein.	tRNA pseudouridine 55 synthase; Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.	0.808
TAM4_577	rpl21e	TAM4_577	TAM4_962	Predicted RNA-binding protein.	LSU ribosomal protein L21e; Belongs to the eukaryotic ribosomal protein eL21 family.	0.937
TAM4_577	rsmA	TAM4_577	TAM4_2323	Predicted RNA-binding protein.	Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.	0.910
TAM4_577	spt4	TAM4_577	TAM4_736	Predicted RNA-binding protein.	DNA-directed RNA polymerase subunit E'; Stimulates transcription elongation; Belongs to the archaeal Spt4 family.	0.672
TAM4_823	TAM4_577	TAM4_823	TAM4_577	DNA-directed RNA polymerase subunit F.	Predicted RNA-binding protein.	0.884
TAM4_823	pus10	TAM4_823	TAM4_636	DNA-directed RNA polymerase subunit F.	tRNA pseudouridine 55 synthase; Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.	0.807
TAM4_823	rpl21e	TAM4_823	TAM4_962	DNA-directed RNA polymerase subunit F.	LSU ribosomal protein L21e; Belongs to the eukaryotic ribosomal protein eL21 family.	0.945
TAM4_823	rsmA	TAM4_823	TAM4_2323	DNA-directed RNA polymerase subunit F.	Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.	0.895
TAM4_823	spt4	TAM4_823	TAM4_736	DNA-directed RNA polymerase subunit F.	DNA-directed RNA polymerase subunit E'; Stimulates transcription elongation; Belongs to the archaeal Spt4 family.	0.789
cca	TAM4_577	TAM4_1025	TAM4_577	tRNA nucleotidyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.	Predicted RNA-binding protein.	0.665
cca	dnaG	TAM4_1025	TAM4_1737	tRNA nucleotidyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.	DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.	0.644
cca	eif5a	TAM4_1025	TAM4_780	tRNA nucleotidyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.	Eukaryotic translation initiation factor eIF-5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.	0.457
cca	nac	TAM4_1025	TAM4_2454	tRNA nucleotidyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.	Nascent polypeptide-associated complex protein; Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family.	0.711
cca	polC	TAM4_1025	TAM4_1407	tRNA nucleotidyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.	Archaeal DNA polymerase II large subunit; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.	0.514