STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TAM4_782Hypothetical protein, conserved protein associated with acetyl-CoA C-acyltransferase. (134 aa)    
Predicted Functional Partners:
TAM4_466
3-ketoacyl-CoA thiolase.
 
 
 0.999
TAM4_592
Hydroxymethylglutaryl-CoA synthase; Belongs to the thiolase-like superfamily. UPF0219 family.
 
 
 0.996
vapC-9
Putative PIN domain protein; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family.
       0.656
TAM4_2461
Hypothetical protein.
       0.655
TAM4_1049
HTH-domain protein.
 
    0.636
flpA
rRNA 2'-O-methyltransferase fibrillarin; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family.
       0.558
TAM4_971
rRNA biogenesis protein Nop5/Nop56.
       0.558
TAM4_589
Translin.
  
     0.413
Your Current Organism:
Thermococcus sp. AM4
NCBI taxonomy Id: 246969
Other names: T. sp. AM4
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