Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NFA_32030Putative sugar kinase. (294 aa)    
Predicted Functional Partners:
NFA_32040
Hypothetical protein.
       0.737
fruA
Putative PTS fructose-specific enzyme IIABC.
     
 0.582
hisA
Putative phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
  
    0.531
NFA_14380
Putative acyl-CoA synthetase.
 
 
 0.487
NFA_32050
Hypothetical protein.
       0.464
NFA_25490
Putative nucleoside hydrolase.
  
  
 0.426
apt
Putative adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
  
 
 0.421
ribH2
Putative riboflavin synthase beta subunit; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
  
  
 0.405
ribH
Putative riboflavin synthase beta subunit; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
  
  
 0.405
mtnA
Putative initiation factor eIF-2B alpha subunit homolog; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
 
 
 0.403
Your Current Organism:
Nocardia farcinica
NCBI taxonomy Id: 247156
Other names: N. farcinica IFM 10152, Nocardia farcinica IFM 10152, Nocardia farcinica str. IFM 10152, Nocardia farcinica strain IFM 10152
Server load: low (16%) [HD]