node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EAW30001.1 | EAW30522.1 | GP2143_01110 | GP2143_00247 | COG0457 FOG: TPR repeat. | Peptidase S1, chymotrypsin:PDZ/DHR/GLGF; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain. | 0.592 |
EAW30001.1 | EAW32914.1 | GP2143_01110 | GP2143_16701 | COG0457 FOG: TPR repeat. | COG2319 FOG: WD40 repeat. | 0.863 |
EAW30001.1 | alaS | GP2143_01110 | GP2143_00065 | COG0457 FOG: TPR repeat. | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | 0.881 |
EAW30001.1 | glpK | GP2143_01110 | GP2143_03014 | COG0457 FOG: TPR repeat. | Probable carbohydrate kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.562 |
EAW30522.1 | EAW30001.1 | GP2143_00247 | GP2143_01110 | Peptidase S1, chymotrypsin:PDZ/DHR/GLGF; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain. | COG0457 FOG: TPR repeat. | 0.592 |
EAW30522.1 | EAW30694.1 | GP2143_00247 | GP2143_02184 | Peptidase S1, chymotrypsin:PDZ/DHR/GLGF; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain. | COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins. | 0.899 |
EAW30522.1 | EAW31526.1 | GP2143_00247 | GP2143_08249 | Peptidase S1, chymotrypsin:PDZ/DHR/GLGF; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain. | Sigma factor algU negative regulatory protein MucA; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytop [...] | 0.895 |
EAW30522.1 | EAW31571.1 | GP2143_00247 | GP2143_08474 | Peptidase S1, chymotrypsin:PDZ/DHR/GLGF; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain. | COG1025 Secreted/periplasmic Zn-dependent peptidases, insulinase-like; Belongs to the peptidase M16 family. | 0.634 |
EAW30522.1 | EAW31769.1 | GP2143_00247 | GP2143_04945 | Peptidase S1, chymotrypsin:PDZ/DHR/GLGF; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain. | COG3203 Outer membrane protein (porin). | 0.620 |
EAW30522.1 | EAW32450.1 | GP2143_00247 | GP2143_14381 | Peptidase S1, chymotrypsin:PDZ/DHR/GLGF; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain. | Probable bifunctional P-450:NADPH-P450 reductase; COG2124 Cytochrome P450. | 0.591 |
EAW30522.1 | EAW32914.1 | GP2143_00247 | GP2143_16701 | Peptidase S1, chymotrypsin:PDZ/DHR/GLGF; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain. | COG2319 FOG: WD40 repeat. | 0.592 |
EAW30522.1 | alaS | GP2143_00247 | GP2143_00065 | Peptidase S1, chymotrypsin:PDZ/DHR/GLGF; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain. | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | 0.620 |
EAW30522.1 | glpK | GP2143_00247 | GP2143_03014 | Peptidase S1, chymotrypsin:PDZ/DHR/GLGF; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain. | Probable carbohydrate kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.824 |
EAW30522.1 | secY | GP2143_00247 | GP2143_01405 | Peptidase S1, chymotrypsin:PDZ/DHR/GLGF; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain. | Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.595 |
EAW30694.1 | EAW30522.1 | GP2143_02184 | GP2143_00247 | COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins. | Peptidase S1, chymotrypsin:PDZ/DHR/GLGF; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain. | 0.899 |
EAW30694.1 | EAW31769.1 | GP2143_02184 | GP2143_04945 | COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins. | COG3203 Outer membrane protein (porin). | 0.907 |
EAW30694.1 | secY | GP2143_02184 | GP2143_01405 | COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins. | Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.595 |
EAW31526.1 | EAW30522.1 | GP2143_08249 | GP2143_00247 | Sigma factor algU negative regulatory protein MucA; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytop [...] | Peptidase S1, chymotrypsin:PDZ/DHR/GLGF; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain. | 0.895 |
EAW31571.1 | EAW30522.1 | GP2143_08474 | GP2143_00247 | COG1025 Secreted/periplasmic Zn-dependent peptidases, insulinase-like; Belongs to the peptidase M16 family. | Peptidase S1, chymotrypsin:PDZ/DHR/GLGF; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain. | 0.634 |
EAW31571.1 | EAW32450.1 | GP2143_08474 | GP2143_14381 | COG1025 Secreted/periplasmic Zn-dependent peptidases, insulinase-like; Belongs to the peptidase M16 family. | Probable bifunctional P-450:NADPH-P450 reductase; COG2124 Cytochrome P450. | 0.660 |