STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EAW31230.1Pyruvate phosphate dikinase; COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase. (868 aa)    
Predicted Functional Partners:
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
    
 0.895
EAW31371.1
2-ketoglutarate: NADP oxidoreductase, alpha subunit; COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit.
    
 0.882
EAW30280.1
COG5016 Pyruvate/oxaloacetate carboxyltransferase.
  
 
 0.857
EAW31568.1
Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 
 0.814
EAW29700.1
COG0825 Acetyl-CoA carboxylase alpha subunit.
  
 
 0.800
EAW32084.1
COG0281 Malic enzyme.
   
 
 0.791
EAW31370.1
Ferrodoxin oxidoreductase beta subunit; COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit.
    
 0.788
EAW30437.1
COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family.
     
 0.787
pckA
Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
     
 0.787
EAW32868.1
Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
    
 0.741
Your Current Organism:
gamma proteobacterium HTCC2143
NCBI taxonomy Id: 247633
Other names: Gammaproteobacteria sp. HTCC2143, m. gamma proteobacterium HTCC2143, marine gamma proteobacterium HTCC2143
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