STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EAW32741.1COG0347 Nitrogen regulatory protein PII; Belongs to the P(II) protein family. (112 aa)    
Predicted Functional Partners:
EAW32740.1
Putative ammonium transporter; COG0004 Ammonia permease.
 0.995
EAW31310.1
Ammonium transporter; COG0004 Ammonia permease.
 0.992
EAW33001.1
Two-component sensor NtrB; COG3852 Signal transduction histidine kinase, nitrogen specific.
  
 0.948
EAW30088.1
ATP-binding region, ATPase-like:Histidine kinase A, N-terminal; COG1639 Predicted signal transduction protein.
  
 0.902
glnD
PII uridylyl-transferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
 
 
 0.890
argB
Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
  
 
 
 0.884
argA
Amino-acid N-acetyltransferase; COG0548 Acetylglutamate kinase; Belongs to the acetyltransferase family. ArgA subfamily.
   
 
 0.877
EAW30863.1
Hypothetical protein.
    
 
 0.693
EAW31298.1
Hypothetical protein; COG1397 ADP-ribosylglycohydrolase.
    
 
 0.693
EAW31626.1
Putative glutamate synthase, ferredoxin-dependent; COG0067 Glutamate synthase domain 1.
     
 0.653
Your Current Organism:
gamma proteobacterium HTCC2143
NCBI taxonomy Id: 247633
Other names: Gammaproteobacteria sp. HTCC2143, m. gamma proteobacterium HTCC2143, marine gamma proteobacterium HTCC2143
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