STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EAW33097.1NUDIX hydrolase; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Belongs to the Nudix hydrolase family. (211 aa)    
Predicted Functional Partners:
EAW33096.1
COG2366 Protein related to penicillin acylase.
       0.718
EAW33098.1
Hypothetical protein; COG3806 Anti-sigma factor.
       0.651
EAW31442.1
Competence/damage-inducible protein CinA; COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; Belongs to the CinA family.
    
  0.630
EAW29906.1
Ribonucleotide-diphosphate reductase alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
    
  0.627
EAW31748.1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
 0.620
EAW31001.1
Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
    
  0.616
EAW31886.1
Putative oxidoreductase; COG0778 Nitroreductase.
  
  
  0.567
EAW31371.1
2-ketoglutarate: NADP oxidoreductase, alpha subunit; COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit.
    
 0.559
EAW30774.1
Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC and GAF sensor(s); COG2199 FOG: GGDEF domain.
   
 
  0.518
EAW33174.1
COG0439 Biotin carboxylase.
  
  
  0.489
Your Current Organism:
gamma proteobacterium HTCC2143
NCBI taxonomy Id: 247633
Other names: Gammaproteobacteria sp. HTCC2143, m. gamma proteobacterium HTCC2143, marine gamma proteobacterium HTCC2143
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.