Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tolQProtein TolQ; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. (236 aa)    
Predicted Functional Partners:
tolR
Protein TolR; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
 
 
 0.991
tolB
Tol-Pal system beta propeller repeat protein TolB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
 
  
 0.981
tolA
Protein TolA; [M] COG0810 Periplasmic protein TonB, links inner and outer membranes.
  
 
 0.956
EEB76803.1
Transport energizing protein, ExbD/TolR family; [U] COG0848 Biopolymer transport protein.
 
 
 0.932
EEB77350.1
Transport energizing protein, ExbD/TolR family; [U] COG0848 Biopolymer transport protein.
 
 
 0.922
EEB79719.1
Transport energizing protein, ExbD/TolR family; [U] COG0848 Biopolymer transport protein.
 
 
 0.908
EEB77160.1
Hypothetical protein; [U] COG0823 Periplasmic component of the Tol biopolymer transport system; WD40-like Beta Propeller Repeat.
 
  
 0.903
pal
Peptidoglycan-associated lipoprotein, putative; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
 
   
 0.901
ybgC
Tol-pal system-associated acyl-CoA thioesterase; [R] COG0824 Predicted thioesterase.
  
  
 0.868
EEB77414.1
TonB family C-terminal domain protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
  
 
 0.858
Your Current Organism:
gamma proteobacterium HTCC2148
NCBI taxonomy Id: 247634
Other names: m. gamma proteobacterium HTCC2148, marine gamma proteobacterium HTCC2148
Server load: low (14%) [HD]