node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EEB78576.1 | EEB78577.1 | GPB2148_1474 | GPB2148_1475 | Conserved domain protein; [S] COG2035 Predicted membrane protein. | M23 peptidase domain protein; [M] COG0739 Membrane proteins related to metalloendopeptidases. | 0.658 |
EEB78576.1 | eno | GPB2148_1474 | GPB2148_1428 | Conserved domain protein; [S] COG2035 Predicted membrane protein. | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. | 0.648 |
EEB78576.1 | ftsB | GPB2148_1474 | GPB2148_1619 | Conserved domain protein; [S] COG2035 Predicted membrane protein. | Septum formation initiator subfamily protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | 0.681 |
EEB78576.1 | ispD | GPB2148_1474 | GPB2148_1378 | Conserved domain protein; [S] COG2035 Predicted membrane protein. | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). | 0.713 |
EEB78576.1 | ispF | GPB2148_1474 | GPB2148_1438 | Conserved domain protein; [S] COG2035 Predicted membrane protein. | 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). | 0.713 |
EEB78576.1 | kdsA | GPB2148_1474 | GPB2148_1472 | Conserved domain protein; [S] COG2035 Predicted membrane protein. | [E] COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; Belongs to the KdsA family. | 0.605 |
EEB78576.1 | pcm | GPB2148_1474 | GPB2148_1500 | Conserved domain protein; [S] COG2035 Predicted membrane protein. | protein-L-isoaspartate O-methyltransferase; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins. | 0.828 |
EEB78576.1 | pyrG | GPB2148_1474 | GPB2148_1376 | Conserved domain protein; [S] COG2035 Predicted membrane protein. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.545 |
EEB78576.1 | truD | GPB2148_1474 | GPB2148_1524 | Conserved domain protein; [S] COG2035 Predicted membrane protein. | tRNA pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family. | 0.687 |
EEB78577.1 | EEB78576.1 | GPB2148_1475 | GPB2148_1474 | M23 peptidase domain protein; [M] COG0739 Membrane proteins related to metalloendopeptidases. | Conserved domain protein; [S] COG2035 Predicted membrane protein. | 0.658 |
EEB78577.1 | eno | GPB2148_1475 | GPB2148_1428 | M23 peptidase domain protein; [M] COG0739 Membrane proteins related to metalloendopeptidases. | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. | 0.548 |
EEB78577.1 | ftsB | GPB2148_1475 | GPB2148_1619 | M23 peptidase domain protein; [M] COG0739 Membrane proteins related to metalloendopeptidases. | Septum formation initiator subfamily protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | 0.577 |
EEB78577.1 | ispD | GPB2148_1475 | GPB2148_1378 | M23 peptidase domain protein; [M] COG0739 Membrane proteins related to metalloendopeptidases. | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). | 0.578 |
EEB78577.1 | ispF | GPB2148_1475 | GPB2148_1438 | M23 peptidase domain protein; [M] COG0739 Membrane proteins related to metalloendopeptidases. | 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). | 0.578 |
EEB78577.1 | kdsA | GPB2148_1475 | GPB2148_1472 | M23 peptidase domain protein; [M] COG0739 Membrane proteins related to metalloendopeptidases. | [E] COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; Belongs to the KdsA family. | 0.480 |
EEB78577.1 | pcm | GPB2148_1475 | GPB2148_1500 | M23 peptidase domain protein; [M] COG0739 Membrane proteins related to metalloendopeptidases. | protein-L-isoaspartate O-methyltransferase; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins. | 0.708 |
EEB78577.1 | pyrG | GPB2148_1475 | GPB2148_1376 | M23 peptidase domain protein; [M] COG0739 Membrane proteins related to metalloendopeptidases. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.441 |
EEB78577.1 | truD | GPB2148_1475 | GPB2148_1524 | M23 peptidase domain protein; [M] COG0739 Membrane proteins related to metalloendopeptidases. | tRNA pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family. | 0.529 |
eno | EEB78576.1 | GPB2148_1428 | GPB2148_1474 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. | Conserved domain protein; [S] COG2035 Predicted membrane protein. | 0.648 |
eno | EEB78577.1 | GPB2148_1428 | GPB2148_1475 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. | M23 peptidase domain protein; [M] COG0739 Membrane proteins related to metalloendopeptidases. | 0.548 |