STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EEB78470.1Amidohydrolase family protein; [E] COG0066 3-isopropylmalate dehydratase small subunit. (560 aa)    
Predicted Functional Partners:
EEB77122.1
LysM domain protein; [S] COG1652 Uncharacterized protein containing LysM domain.
   
    0.737
EEB78449.1
Hypothetical protein.
       0.697
wrbA
NAD(P)H:quinone oxidoreductase, type IV; [R] COG0655 Multimeric flavodoxin WrbA; Belongs to the WrbA family.
   
  
 0.597
EEB79996.1
Hypothetical protein; [C] COG0716 Flavodoxins.
   
  
 0.597
EEB78362.1
Amidohydrolase family, putative; [F] COG0044 Dihydroorotase and related cyclic amidohydrolases.
 
     0.552
EEB78380.1
Hypothetical protein.
       0.476
gyrA
DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
  
    0.472
parC
DNA topoisomerase IV, A subunit; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
  
    0.472
EEB80260.1
Putative phospholipid-binding domain family protein; [R] COG2823 Predicted periplasmic or secreted lipoprotein.
   
  
 0.408
Your Current Organism:
gamma proteobacterium HTCC2148
NCBI taxonomy Id: 247634
Other names: m. gamma proteobacterium HTCC2148, marine gamma proteobacterium HTCC2148
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