STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EEB80122.1Hypothetical protein; [G] COG0279 Phosphoheptose isomerase. (215 aa)    
Predicted Functional Partners:
EEB77067.1
Histidinol-phosphate phosphatase family domain protein; [E] COG0241 Histidinol phosphatase and related phosphatases.
 
 
 0.981
hldE
Kinase, pfkB family; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family.
 
  
 0.972
EEB80260.1
Putative phospholipid-binding domain family protein; [R] COG2823 Predicted periplasmic or secreted lipoprotein.
  
    0.871
EEB78190.1
Cytidylyltransferase, putative; [MI] COG0615 Cytidylyltransferase.
 
  
 0.869
EEB80359.1
Conserved hypothetical protein TIGR00252; [L] COG0792 Predicted endonuclease distantly related to archaeal Holliday junction resolvase; Belongs to the UPF0102 family.
  
  
 0.860
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.
    
 
 0.848
rfaF_1
Lipopolysaccharide heptosyltransferase II; [M] COG0859 ADP-heptose:LPS heptosyltransferase.
 
  
 0.815
EEB80420.1
[R] COG3107 Putative lipoprotein.
  
    0.787
rfaF_2
Lipopolysaccharide heptosyltransferase II; [M] COG0859 ADP-heptose:LPS heptosyltransferase.
 
  
 0.787
hda
DnaA regulatory inactivator Hda; [L] COG0593 ATPase involved in DNA replication initiation; Belongs to the DnaA family. HdA subfamily.
   
 
 0.766
Your Current Organism:
gamma proteobacterium HTCC2148
NCBI taxonomy Id: 247634
Other names: m. gamma proteobacterium HTCC2148, marine gamma proteobacterium HTCC2148
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