Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EEB77179.1Conserved hypothetical protein. (321 aa)    
Predicted Functional Partners:
EEB77177.1
Hypothetical protein.
 
     0.950
EEB78382.1
Conserved hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
 
     0.811
EEB78439.1
Methionine synthase, vitamin-B12 independent, putative; [E] COG0620 Methionine synthase II (cobalamin-independent).
 
     0.789
EEB78329.1
Conserved hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
 
     0.788
EEB78366.1
Cupin domain protein; [S] COG1917 Uncharacterized conserved protein, contains double-stranded beta-helix domain.
 
     0.781
EEB78381.1
Conserved hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
 
     0.780
EEB78320.1
Hydrolase, alpha/beta fold family, putative; [R] COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).
 
     0.733
hisD_2
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
 
     0.671
EEB78376.1
Periplasmic binding proteins and sugar binding domain of the LacI family, putative; [K] COG1609 Transcriptional regulators.
 
     0.593
EEB77108.1
Hypothetical protein.
  
     0.493
Your Current Organism:
gamma proteobacterium HTCC2148
NCBI taxonomy Id: 247634
Other names: m. gamma proteobacterium HTCC2148, marine gamma proteobacterium HTCC2148
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