EEB80386.1 protein (gamma proteobacterium HTCC2148)

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EEB80386.1

RNA methyltransferase, TrmH family; [J] COG0219 Predicted rRNA methylase (SpoU class). (215 aa)

Predicted Functional Partners:

rplM

0.872

ylqF

0.863

trmE

0.863

rsfS

0.860

rplQ

0.856

rplC

0.847

rplK

0.847

ysxC

0.847

rplX

0.846

truD

0.845

Your Current Organism:

gamma proteobacterium HTCC2148

NCBI taxonomy Id: 247634
Other names: m. gamma proteobacterium HTCC2148, marine gamma proteobacterium HTCC2148

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EEB80386.1	rplC	GPB2148_3203	GPB2148_1098	RNA methyltransferase, TrmH family; [J] COG0219 Predicted rRNA methylase (SpoU class).	Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.	0.847
EEB80386.1	rplK	GPB2148_3203	GPB2148_3407	RNA methyltransferase, TrmH family; [J] COG0219 Predicted rRNA methylase (SpoU class).	Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.	0.847
EEB80386.1	rplM	GPB2148_3203	GPB2148_3305	RNA methyltransferase, TrmH family; [J] COG0219 Predicted rRNA methylase (SpoU class).	Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	0.872
EEB80386.1	rplQ	GPB2148_3203	GPB2148_1119	RNA methyltransferase, TrmH family; [J] COG0219 Predicted rRNA methylase (SpoU class).	[J] COG0203 Ribosomal protein L17; Belongs to the bacterial ribosomal protein bL17 family.	0.856
EEB80386.1	rplX	GPB2148_3203	GPB2148_1090	RNA methyltransferase, TrmH family; [J] COG0219 Predicted rRNA methylase (SpoU class).	Ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.	0.846
EEB80386.1	rsfS	GPB2148_3203	GPB2148_207	RNA methyltransferase, TrmH family; [J] COG0219 Predicted rRNA methylase (SpoU class).	Iojap family protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.	0.860
EEB80386.1	trmE	GPB2148_3203	GPB2148_352	RNA methyltransferase, TrmH family; [J] COG0219 Predicted rRNA methylase (SpoU class).	tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.	0.863
EEB80386.1	truD	GPB2148_3203	GPB2148_1524	RNA methyltransferase, TrmH family; [J] COG0219 Predicted rRNA methylase (SpoU class).	tRNA pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family.	0.845
EEB80386.1	ylqF	GPB2148_3203	GPB2148_1495	RNA methyltransferase, TrmH family; [J] COG0219 Predicted rRNA methylase (SpoU class).	Putative GTPase; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.	0.863
EEB80386.1	ysxC	GPB2148_3203	GPB2148_457	RNA methyltransferase, TrmH family; [J] COG0219 Predicted rRNA methylase (SpoU class).	Putative GTPase; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.	0.847
rplC	EEB80386.1	GPB2148_1098	GPB2148_3203	Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.	RNA methyltransferase, TrmH family; [J] COG0219 Predicted rRNA methylase (SpoU class).	0.847
rplC	rplK	GPB2148_1098	GPB2148_3407	Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.	Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.	0.999
rplC	rplM	GPB2148_1098	GPB2148_3305	Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.	Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	0.999
rplC	rplQ	GPB2148_1098	GPB2148_1119	Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.	[J] COG0203 Ribosomal protein L17; Belongs to the bacterial ribosomal protein bL17 family.	0.997
rplC	rplX	GPB2148_1098	GPB2148_1090	Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.	Ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.	0.999
rplC	rsfS	GPB2148_1098	GPB2148_207	Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.	Iojap family protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.	0.962
rplC	trmE	GPB2148_1098	GPB2148_352	Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.	tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.	0.927
rplC	truD	GPB2148_1098	GPB2148_1524	Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.	tRNA pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family.	0.927
rplC	ylqF	GPB2148_1098	GPB2148_1495	Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.	Putative GTPase; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.	0.968
rplC	ysxC	GPB2148_1098	GPB2148_457	Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.	Putative GTPase; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.	0.943