STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EEB78367.1[R] COG2070 Dioxygenases related to 2-nitropropane dioxygenase. (374 aa)    
Predicted Functional Partners:
EEB78297.1
Conserved domain protein, putative; [R] COG1545 Predicted nucleic-acid-binding protein containing a Zn-ribbon.
 
     0.678
guaA
GMP synthase, C-terminal domain protein; Catalyzes the synthesis of GMP from XMP.
    
  0.646
EEB78408.1
Conserved domain protein, putative; [R] COG1545 Predicted nucleic-acid-binding protein containing a Zn-ribbon.
 
     0.641
EEB78443.1
Hypothetical protein; [I] COG0183 Acetyl-CoA acetyltransferase.
 
    0.640
EEB78335.1
Hypothetical protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
 
     0.636
EEB78398.1
Hypothetical protein; [I] COG2030 Acyl dehydratase.
  
 
  0.591
pcaC
[S] COG0599 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit.
  
  
  0.591
EEB78474.1
Putative MaoC like domain protein; [I] COG2030 Acyl dehydratase.
  
 
  0.574
EEB78337.1
Hypothetical protein; [I] COG0183 Acetyl-CoA acetyltransferase.
 
    0.573
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
  0.571
Your Current Organism:
gamma proteobacterium HTCC2148
NCBI taxonomy Id: 247634
Other names: m. gamma proteobacterium HTCC2148, marine gamma proteobacterium HTCC2148
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