node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EEB77818.1 | EEB77836.1 | GPB2148_928 | GPB2148_946 | PhoH family protein; [T] COG1702 Phosphate starvation-inducible protein PhoH, predicted ATPase. | [R] COG0517 FOG: CBS domain. | 0.893 |
EEB77818.1 | clpX | GPB2148_928 | GPB2148_3465 | PhoH family protein; [T] COG1702 Phosphate starvation-inducible protein PhoH, predicted ATPase. | ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.621 |
EEB77818.1 | era | GPB2148_928 | GPB2148_1878 | PhoH family protein; [T] COG1702 Phosphate starvation-inducible protein PhoH, predicted ATPase. | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.573 |
EEB77818.1 | holA | GPB2148_928 | GPB2148_1072 | PhoH family protein; [T] COG1702 Phosphate starvation-inducible protein PhoH, predicted ATPase. | [L] COG1466 DNA polymerase III, delta subunit. | 0.552 |
EEB77818.1 | leuS | GPB2148_928 | GPB2148_1066 | PhoH family protein; [T] COG1702 Phosphate starvation-inducible protein PhoH, predicted ATPase. | [J] COG0060 Isoleucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.561 |
EEB77818.1 | lnt | GPB2148_928 | GPB2148_1067 | PhoH family protein; [T] COG1702 Phosphate starvation-inducible protein PhoH, predicted ATPase. | Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. | 0.895 |
EEB77818.1 | lptE | GPB2148_928 | GPB2148_934 | PhoH family protein; [T] COG1702 Phosphate starvation-inducible protein PhoH, predicted ATPase. | Rare lipoprotein B family protein; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane. | 0.537 |
EEB77818.1 | miaB | GPB2148_928 | GPB2148_1006 | PhoH family protein; [T] COG1702 Phosphate starvation-inducible protein PhoH, predicted ATPase. | tRNA-i(6)A37 thiotransferase enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. | 0.685 |
EEB77818.1 | recO | GPB2148_928 | GPB2148_1693 | PhoH family protein; [T] COG1702 Phosphate starvation-inducible protein PhoH, predicted ATPase. | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | 0.805 |
EEB77818.1 | ybeY | GPB2148_928 | GPB2148_927 | PhoH family protein; [T] COG1702 Phosphate starvation-inducible protein PhoH, predicted ATPase. | Conserved hypothetical protein TIGR00043, putative; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.983 |
EEB77836.1 | EEB77818.1 | GPB2148_946 | GPB2148_928 | [R] COG0517 FOG: CBS domain. | PhoH family protein; [T] COG1702 Phosphate starvation-inducible protein PhoH, predicted ATPase. | 0.893 |
EEB77836.1 | holA | GPB2148_946 | GPB2148_1072 | [R] COG0517 FOG: CBS domain. | [L] COG1466 DNA polymerase III, delta subunit. | 0.529 |
EEB77836.1 | leuS | GPB2148_946 | GPB2148_1066 | [R] COG0517 FOG: CBS domain. | [J] COG0060 Isoleucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.561 |
EEB77836.1 | lnt | GPB2148_946 | GPB2148_1067 | [R] COG0517 FOG: CBS domain. | Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. | 0.896 |
EEB77836.1 | lptE | GPB2148_946 | GPB2148_934 | [R] COG0517 FOG: CBS domain. | Rare lipoprotein B family protein; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane. | 0.545 |
EEB77836.1 | miaB | GPB2148_946 | GPB2148_1006 | [R] COG0517 FOG: CBS domain. | tRNA-i(6)A37 thiotransferase enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. | 0.681 |
EEB77836.1 | ybeY | GPB2148_946 | GPB2148_927 | [R] COG0517 FOG: CBS domain. | Conserved hypothetical protein TIGR00043, putative; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.945 |
clpX | EEB77818.1 | GPB2148_3465 | GPB2148_928 | ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | PhoH family protein; [T] COG1702 Phosphate starvation-inducible protein PhoH, predicted ATPase. | 0.621 |
era | EEB77818.1 | GPB2148_1878 | GPB2148_928 | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | PhoH family protein; [T] COG1702 Phosphate starvation-inducible protein PhoH, predicted ATPase. | 0.573 |
era | recO | GPB2148_1878 | GPB2148_1693 | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | 0.928 |