STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OJG45093.1Cyclopropane-fatty-acyl-phospholipid synthase. (387 aa)    
Predicted Functional Partners:
OJG46755.1
Hypothetical protein.
  
 
 0.753
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
   
 
 0.691
OJG45115.1
Methyltransferase.
  
 
 0.573
OJG45092.1
Hypothetical protein.
       0.531
fabH
3-oxoacyl-[acyl-carrier-protein] synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
     
 0.524
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.514
OJG45621.1
8-amino-7-oxononanoate synthase.
    
 0.514
OJG46080.1
FAD dependent oxidoreductase.
    
  0.510
OJG45094.1
MarR family transcriptional regulator.
       0.497
acpP-2
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
     
 0.481
Your Current Organism:
Enterococcus hermanniensis
NCBI taxonomy Id: 249189
Other names: CCUG 48100, DSM 17122, E. hermanniensis, Enterococcus hermanniensis Koort et al. 2004, LMG 12317, LMG:12317
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