STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHN67445.1Methyltransferase domain-containing protein. (254 aa)    
Predicted Functional Partners:
SHN61102.1
ABC1 family protein.
    
 0.697
SHN71620.1
2-polyprenyl-6-methoxyphenol hydroxylase.
 
 
 0.693
kmo
Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid; Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
   
 0.636
SHN67437.1
Hypothetical protein.
       0.608
SHN70137.1
Glycine dehydrogenase; Belongs to the GcvP family.
   
 
  0.552
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
  0.548
SHN72224.1
Magnesium chelatase subunit I.
   
 
 0.511
SHN76566.1
Thiopurine S-methyltransferase (TPMT).
  
 
  0.481
SHN59818.1
Radical SAM superfamily enzyme YgiQ, UPF0313 family.
   
 
 0.475
SHN53039.1
Methyltransferase, FkbM family.
    
 0.470
Your Current Organism:
Flavobacterium fryxellicola
NCBI taxonomy Id: 249352
Other names: CIP 108325, DSM 16209, F. fryxellicola, Flavobacterium fryxellicola Van Trappen et al. 2005 emend. Hahnke et al. 2016, LMG 22022, LMG:22022
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