STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aptAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (170 aa)    
Predicted Functional Partners:
guaA
GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.
  
 0.986
SHN60240.1
Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
 0.967
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
 
 0.958
purH
Phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase.
  
 0.949
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
  
 0.943
SHN78560.1
Purine-nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
  
 
 0.930
SHN70064.1
Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
 0.916
surE
5'-nucleotidase /3'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
 0.903
SHN49608.1
Deoxyadenosine/deoxycytidine kinase.
  
 
 0.901
SHN72842.1
5'-nucleotidase; Belongs to the 5'-nucleotidase family.
    
 0.892
Your Current Organism:
Flavobacterium fryxellicola
NCBI taxonomy Id: 249352
Other names: CIP 108325, DSM 16209, F. fryxellicola, Flavobacterium fryxellicola Van Trappen et al. 2005 emend. Hahnke et al. 2016, LMG 22022, LMG:22022
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.