node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
gll0521 | gll1496 | gene:10757993 | gene:10758985 | ORF_ID:gll0521; probable transglycosylase. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.747 |
gll0521 | gll2215 | gene:10757993 | gene:10759710 | ORF_ID:gll0521; probable transglycosylase. | glutamine-fructose-6-P-aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.780 |
gll0521 | gll3738 | gene:10757993 | gene:10761254 | ORF_ID:gll0521; probable transglycosylase. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.773 |
gll0521 | glr3125 | gene:10757993 | gene:10760631 | ORF_ID:gll0521; probable transglycosylase. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.844 |
gll0521 | glr3818 | gene:10757993 | gene:10761335 | ORF_ID:gll0521; probable transglycosylase. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.789 |
gll0521 | murC | gene:10757993 | gene:10759811 | ORF_ID:gll0521; probable transglycosylase. | UDP-N-acetylmuramate-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.849 |
gll0521 | murD | gene:10757993 | gene:10761248 | ORF_ID:gll0521; probable transglycosylase. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.774 |
gll0521 | murE | gene:10757993 | gene:10761004 | ORF_ID:gll0521; probable transglycosylase. | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.797 |
gll1496 | gll0521 | gene:10758985 | gene:10757993 | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | ORF_ID:gll0521; probable transglycosylase. | 0.747 |
gll1496 | gll2215 | gene:10758985 | gene:10759710 | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | glutamine-fructose-6-P-aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.807 |
gll1496 | gll3738 | gene:10758985 | gene:10761254 | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.825 |
gll1496 | glr0532 | gene:10758985 | gene:10758005 | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | dITP/XTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.928 |
gll1496 | glr3125 | gene:10758985 | gene:10760631 | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.711 |
gll1496 | glr3818 | gene:10758985 | gene:10761335 | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.813 |
gll1496 | murC | gene:10758985 | gene:10759811 | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | UDP-N-acetylmuramate-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.780 |
gll1496 | murD | gene:10758985 | gene:10761248 | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.987 |
gll1496 | murE | gene:10758985 | gene:10761004 | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.702 |
gll1496 | purQ | gene:10758985 | gene:10758808 | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | Phosphoribosylformyl glycinamidine synthetase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] | 0.900 |
gll2215 | gll0521 | gene:10759710 | gene:10757993 | glutamine-fructose-6-P-aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | ORF_ID:gll0521; probable transglycosylase. | 0.780 |
gll2215 | gll1496 | gene:10759710 | gene:10758985 | glutamine-fructose-6-P-aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.807 |