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hisH protein (Gloeobacter violaceus) - STRING interaction network
"hisH" - Imidazole glycerol phosphate synthase subunit HisH in Gloeobacter violaceus
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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hisHImidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (226 aa)    
Predicted Functional Partners:
hisF
Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (254 aa)
  0.999
hisA
Phosphorybosilformimino-5-amino-phosphorybosil-4-imidazolecarboxamideisomerase (255 aa)
 
  0.997
hisB
Imidazoleglycerol-phosphate dehydratase (197 aa)
 
 
  0.996
hisI
phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphohydrolase (218 aa)
 
   
  0.991
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (445 aa)
 
   
  0.979
gll1323
Histidinol-phosphate aminotransferase (353 aa)
 
   
  0.957
hisG
ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N’-(5’-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (214 aa)
 
   
  0.943
gll3423
Threonine-phosphate decarboxylase (375 aa)
 
   
  0.933
gll2475
Histidinol-phosphate aminotransferase (410 aa)
 
   
  0.929
purH
Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (499 aa)
   
 
  0.898
Your Current Organism:
Gloeobacter violaceus
NCBI taxonomy Id: 251221
Other names: G. violaceus, G. violaceus PCC 7421, Gloeobacter, Gloeobacter violaceus, Gloeobacter violaceus ATCC 29082, Gloeobacter violaceus PCC 7421, Gloeobacter violaceus str. PCC 7421, Gloeobacter violaceus strain PCC 7421, Gloeobacterales, Gloeobacterales Cavalier-Smith 2002, Gloeobacteria, Gloeobacteria Cavalier-Smith 2002
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