node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
glr0755 | trpF | gene:10758232 | gene:10758231 | ORF_ID:glr0755; hypothetical protein. | N-(5'-phosphoribosyl)anthranilate isomerase; ORF_ID:gll0754; Belongs to the TrpF family. | 0.579 |
glr1559 | hisIE | gene:10759048 | gene:10758690 | ORF_ID:glr1559; hypothetical protein. | phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphohydrolase; ORF_ID:glr1211; histidine biosynthesis bifunctional; In the C-terminal section; belongs to the PRA-PH family. | 0.563 |
glr1559 | trpA | gene:10759048 | gene:10760112 | ORF_ID:glr1559; hypothetical protein. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.954 |
glr1559 | trpB | gene:10759048 | gene:10760261 | ORF_ID:glr1559; hypothetical protein. | Tryptophan synthase beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.949 |
glr1559 | trpC | gene:10759048 | gene:10760056 | ORF_ID:glr1559; hypothetical protein. | Indole-3-glycerol phosphate synthase; ORF_ID:gll2556; Belongs to the TrpC family. | 0.954 |
glr1559 | trpE | gene:10759048 | gene:10758234 | ORF_ID:glr1559; hypothetical protein. | Anthranilate synthase component; ORF_ID:gll0757. | 0.977 |
glr1559 | trpE-2 | gene:10759048 | gene:10759208 | ORF_ID:glr1559; hypothetical protein. | Anthranilate synthetase alpha-subunit; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high conc [...] | 0.978 |
glr1559 | trpF | gene:10759048 | gene:10758231 | ORF_ID:glr1559; hypothetical protein. | N-(5'-phosphoribosyl)anthranilate isomerase; ORF_ID:gll0754; Belongs to the TrpF family. | 0.953 |
glr1559 | trpG | gene:10759048 | gene:10758361 | ORF_ID:glr1559; hypothetical protein. | Anthranilate synthase component II; ORF_ID:glr0883. | 0.940 |
hisIE | glr1559 | gene:10758690 | gene:10759048 | phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphohydrolase; ORF_ID:glr1211; histidine biosynthesis bifunctional; In the C-terminal section; belongs to the PRA-PH family. | ORF_ID:glr1559; hypothetical protein. | 0.563 |
hisIE | trpA | gene:10758690 | gene:10760112 | phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphohydrolase; ORF_ID:glr1211; histidine biosynthesis bifunctional; In the C-terminal section; belongs to the PRA-PH family. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.660 |
hisIE | trpB | gene:10758690 | gene:10760261 | phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphohydrolase; ORF_ID:glr1211; histidine biosynthesis bifunctional; In the C-terminal section; belongs to the PRA-PH family. | Tryptophan synthase beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.644 |
hisIE | trpC | gene:10758690 | gene:10760056 | phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphohydrolase; ORF_ID:glr1211; histidine biosynthesis bifunctional; In the C-terminal section; belongs to the PRA-PH family. | Indole-3-glycerol phosphate synthase; ORF_ID:gll2556; Belongs to the TrpC family. | 0.582 |
hisIE | trpD | gene:10758690 | gene:10760298 | phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphohydrolase; ORF_ID:glr1211; histidine biosynthesis bifunctional; In the C-terminal section; belongs to the PRA-PH family. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.563 |
hisIE | trpE | gene:10758690 | gene:10758234 | phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphohydrolase; ORF_ID:glr1211; histidine biosynthesis bifunctional; In the C-terminal section; belongs to the PRA-PH family. | Anthranilate synthase component; ORF_ID:gll0757. | 0.474 |
hisIE | trpE-2 | gene:10758690 | gene:10759208 | phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphohydrolase; ORF_ID:glr1211; histidine biosynthesis bifunctional; In the C-terminal section; belongs to the PRA-PH family. | Anthranilate synthetase alpha-subunit; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high conc [...] | 0.547 |
hisIE | trpF | gene:10758690 | gene:10758231 | phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphohydrolase; ORF_ID:glr1211; histidine biosynthesis bifunctional; In the C-terminal section; belongs to the PRA-PH family. | N-(5'-phosphoribosyl)anthranilate isomerase; ORF_ID:gll0754; Belongs to the TrpF family. | 0.641 |
hisIE | trpG | gene:10758690 | gene:10758361 | phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphohydrolase; ORF_ID:glr1211; histidine biosynthesis bifunctional; In the C-terminal section; belongs to the PRA-PH family. | Anthranilate synthase component II; ORF_ID:glr0883. | 0.492 |
trpA | glr1559 | gene:10760112 | gene:10759048 | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | ORF_ID:glr1559; hypothetical protein. | 0.954 |
trpA | hisIE | gene:10760112 | gene:10758690 | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphohydrolase; ORF_ID:glr1211; histidine biosynthesis bifunctional; In the C-terminal section; belongs to the PRA-PH family. | 0.660 |