STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FHL15_000532Uncharacterized protein. (992 aa)    
Predicted Functional Partners:
FHL15_002527
Thymidylat_synt domain-containing protein.
  
 
 0.743
FHL15_011088
Thymidylate_kin domain-containing protein.
  
 
 0.661
FHL15_006700
S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
    
 0.661
FHL15_004526
Uncharacterized protein.
    
  0.642
NCS6
Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation.
  
 
 0.634
FHL15_011373
Uncharacterized protein.
    
 0.529
FHL15_009336
Metallophos domain-containing protein.
    
 0.529
FHL15_002717
Pribosyltran domain-containing protein.
  
 
  0.526
FHL15_005655
Uncharacterized protein.
  
 
  0.525
FHL15_004320
IU_nuc_hydro domain-containing protein.
    
  0.519
Your Current Organism:
Xylaria flabelliformis
NCBI taxonomy Id: 2512241
Other names: Sphaeria flabelliformis, X. flabelliformis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.