STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Chro_0311PFAM: Protein of unknown function (DUF752); COGs: COG4121 conserved hypothetical protein; InterPro IPR008471; KEGG: ter:Tery_0559 hypothetical protein; PFAM: protein of unknown function DUF752; SPTR: Putative uncharacterized protein. (299 aa)    
Predicted Functional Partners:
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
       0.642
Chro_4169
KEGG: npu:Npun_F4125 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.552
lipA
Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
       0.520
Chro_1564
PFAM: Protein of unknown function (DUF751); InterPro IPR008470; KEGG: npu:Npun_F0702 hypothetical protein; PFAM: protein of unknown function DUF751; SPTR: Putative uncharacterized protein.
  
     0.467
Chro_2589
PFAM: Protein of unknown function (DUF2839); KEGG: cyh:Cyan8802_0653 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.453
miaA
tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.
       0.452
Chro_0314
KEGG: ana:all8565 hypothetical protein; SPTR: All8565 protein.
       0.452
Chro_1682
Hypothetical protein; InterPro IPR020885; KEGG: naz:Aazo_3777 hypothetical protein; SPTR: Putative uncharacterized protein; Belongs to the UPF0367 family.
  
     0.439
Chro_0413
PFAM: Rhodanese-like domain; TIGRFAM: tRNA 2-selenouridine synthase; COGs: COG2603 ATPase; InterPro IPR001763:IPR017582; KEGG: cya:CYA_1917 tRNA 2-selenouridine synthase; SMART: Rhodanese domain protein; SPTR: Putative tRNA 2-selenouridine synthase; TIGRFAM: tRNA 2-selenouridine synthase.
  
   
 0.417
Chro_0851
PFAM: Protein of unknown function (DUF2808); KEGG: npu:Npun_R3476 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.412
Your Current Organism:
Chroococcidiopsis thermalis
NCBI taxonomy Id: 251229
Other names: C. thermalis PCC 7203, Chroococcidiopsis sp. ATCC 27900, Chroococcidiopsis sp. PCC 7203, Chroococcidiopsis thermalis PCC 7203, Chroococcidiopsis thermalis str. PCC 7203
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