STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Chro_0458PFAM: Peptidase family M1; PBS lyase HEAT-like repeat; COGs: COG0308 Aminopeptidase N; InterPro IPR004155:IPR014782:IPR000357; KEGG: npu:Npun_F2817 peptidase M1, membrane alanine aminopeptidase; PFAM: Peptidase M1 membrane alanine aminopeptidase; PBS lyase HEAT domain protein repeat-containing protein; HEAT domain containing protein; SMART: PBS lyase HEAT domain protein repeat-containing protein; SPTR: Peptidase M1, membrane alanine aminopeptidase. (863 aa)    
Predicted Functional Partners:
pepA
Leucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
  
 0.931
gshB
PFAM: Prokaryotic glutathione synthetase, N-terminal domain; Prokaryotic glutathione synthetase, ATP-grasp domain; TIGRFAM: glutathione synthetase, prokaryotic; COGs: COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase); InterPro IPR011761:IPR004215:IPR004218:IPR006284; KEGG: ana:all3859 glutathione synthetase; PFAM: glutathione synthetase ATP-binding; glutathione synthetase domain protein; PRIAM: Glutathione synthase; SPTR: Glutathione synthetase; TIGRFAM: glutathione synthetase; Belongs to the prokaryotic GSH synthase family.
  
  
 0.919
Chro_2891
Gamma-glutamyltransferase 1; PFAM: Gamma-glutamyltranspeptidase; TIGRFAM: gamma-glutamyltranspeptidase; COGs: COG0405 Gamma-glutamyltransferase; InterPro IPR000101; KEGG: bpt:Bpet0836 hypothetical protein; PFAM: gamma-glutamyltranspeptidase; PRIAM: Gamma-glutamyltransferase; SPTR: Gamma-glutamyltranspeptidase; TIGRFAM: gamma-glutamyltransferase.
     
 0.908
Chro_5388
Gamma-glutamyltransferase; PFAM: Gamma-glutamyltranspeptidase; TIGRFAM: gamma-glutamyltranspeptidase; COGs: COG0405 Gamma-glutamyltransferase; InterPro IPR000101; KEGG: cyc:PCC7424_3495 gamma-glutamyltransferase; PFAM: gamma-glutamyltranspeptidase; PRIAM: Gamma-glutamyltransferase; SPTR: Gamma-glutamyltransferase; TIGRFAM: gamma-glutamyltransferase.
     
 0.908
Chro_4219
ChaC family protein; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.
    
  0.900
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.851
Chro_4093
Pyridoxal-5'-phosphate-dependent protein beta subunit; PFAM: Pyridoxal-phosphate dependent enzyme; COGs: COG0031 Cysteine synthase; InterPro IPR001216:IPR001926; KEGG: amr:AM1_5090 cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: Cysteine synthase.
    
 0.833
Chro_5595
Cysteine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; COGs: COG0031 Cysteine synthase; InterPro IPR001216:IPR005856:IPR005859:IPR001926; KEGG: ava:Ava_2508 cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: Cysteine synthase; TIGRFAM: cysteine synthase A; cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
    
 0.833
Chro_2918
PFAM: Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839:IPR004838:IPR001176; KEGG: ter:Tery_2717 aminotransferase; PFAM: aminotransferase class I and II; SPTR: Aminotransferase.
   
 
 0.809
Chro_5233
PFAM: Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR001176:IPR004839:IPR004838; KEGG: npu:Npun_R0187 aspartate aminotransferase; PFAM: aminotransferase class I and II; SPTR: Aminotransferase, class I and II.
   
 
 0.809
Your Current Organism:
Chroococcidiopsis thermalis
NCBI taxonomy Id: 251229
Other names: C. thermalis PCC 7203, Chroococcidiopsis sp. ATCC 27900, Chroococcidiopsis sp. PCC 7203, Chroococcidiopsis thermalis PCC 7203, Chroococcidiopsis thermalis str. PCC 7203
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