STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
Chro_0614CheA signal transduction histidine kinase; PFAM: CheW-like domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Signal transducing histidine kinase, homodimeric domain; Hpt domain; COGs: COG0643 Chemotaxis protein histidine kinase and related kinase; InterProIPR005467:IPR002545:IPR008207:IPR004358:IPR 003594:IPR004105; KEGG: ter:Tery_4224 CheA signal transduction histidine kinases; PFAM: CheW domain protein; ATP-binding region ATPase domain protein; Signal transducing histidine kinase homodimeric; Hpt domain protein; SMART: CheW domain protein; ATP-binding region ATPase dom [...] (816 aa)    
Predicted Functional Partners:
Chro_0615
PFAM: CheW-like domain; COGs: COG0835 Chemotaxis signal transduction protein; InterPro IPR002545; KEGG: ter:Tery_4225 CheW protein; PFAM: CheW domain protein; SMART: CheW domain protein; SPTR: Putative uncharacterized protein.
 0.994
cheB-2
Response regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 0.994
cheB
Response regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 0.991
Chro_3456
PFAM: CheB methylesterase; COGs: COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain; InterPro IPR000673; KEGG: cyc:PCC7424_1189 CheB methylesterase; PFAM: CheB methylesterase; PRIAM: Protein-glutamate methylesterase; SPTR: CheB methylesterase.
 
 0.991
Chro_4926
PFAM: CheB methylesterase; COGs: COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain; InterPro IPR000673; KEGG: npu:Npun_F0262 CheB methylesterase; PFAM: CheB methylesterase; PRIAM: Protein-glutamate methylesterase; SPTR: CheB methylesterase; manually curated.
 
 0.991
Chro_0616
PFAM: HAMP domain; Methyl-accepting chemotaxis protein (MCP) signaling domain; COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR004089:IPR002035:IPR003660:IPR004090; KEGG: ter:Tery_4229 methyl-accepting chemotaxis sensory transducer; PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SPTR: Methyl-accepting chemotaxis protein signaling domain.
 
 0.990
Chro_0250
MCP methyltransferase, CheR-type with PAS/PAC sensor; PFAM: CheR methyltransferase, SAM binding domain; CheR methyltransferase, all-alpha domain; COGs: COG1352 Methylase of chemotaxis methyl-accepting protein; InterPro IPR000780:IPR000014; KEGG: npu:Npun_F0263 MCP methyltransferase, CheR-type with PAS/PAC sensor; PFAM: MCP methyltransferase CheR-type; PRIAM: Protein-glutamate O-methyltransferase; SMART: MCP methyltransferase CheR-type; SPTR: MCP methyltransferase, CheR-type with PAS/PAC sensor; TIGRFAM: PAS sensor protein.
 
 
 0.983
Chro_2025
MCP methyltransferase, CheR-type; PFAM: CheR methyltransferase, SAM binding domain; CheR methyltransferase, all-alpha domain; COGs: COG1352 Methylase of chemotaxis methyl-accepting protein; InterPro IPR000780; KEGG: cyn:Cyan7425_3121 MCP methyltransferase, CheR-type with PAS/PAC sensor; PFAM: MCP methyltransferase CheR-type; PRIAM: Protein-glutamate O-methyltransferase; SMART: MCP methyltransferase CheR-type; SPTR: Putative uncharacterized protein.
 
 
 0.983
Chro_3457
MCP methyltransferase, CheR-type with PAS/PAC sensor; PFAM: CheR methyltransferase, SAM binding domain; Guanylate kinase; CheR methyltransferase, all-alpha domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG1352 Methylase of chemotaxis methyl-accepting protein; InterPro IPR000014:IPR000780:IPR013767:IPR000700; KEGG: cyn:Cyan7425_3121 MCP methyltransferase, CheR-type with PAS/PAC sensor; PFAM: MCP methyltransferase CheR-type; PAS fold domain protein; PRIAM: Protein-glutamate O-methyltransferase; SMART: MCP methyltransferase CheR-type; PAS domain containing protein; SPTR: MCP methyltr [...]
 
 
 0.975
Chro_0015
PFAM: CheW-like domain; COGs: COG0835 Chemotaxis signal transduction protein; InterPro IPR002545; KEGG: amr:AM1_5079 chemotaxis signal transduction protein CheW, putative; PFAM: CheW domain protein; SMART: CheW domain protein; SPTR: Chemotaxis signal transduction protein.
 
 0.973
Your Current Organism:
Chroococcidiopsis thermalis
NCBI taxonomy Id: 251229
Other names: C. thermalis PCC 7203, Chroococcidiopsis sp. ATCC 27900, Chroococcidiopsis sp. PCC 7203, Chroococcidiopsis thermalis PCC 7203, Chroococcidiopsis thermalis str. PCC 7203
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