STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Chro_0719Nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; TIGRFAM: nucleotide sugar dehydrogenase; COGs: COG1004 UDP-glucose 6-dehydrogenase; InterPro IPR017476:IPR001732:IPR014026:IPR014027; KEGG: dsa:Desal_3469 nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; PRIAM: GDP-mannose 6-dehydrogenase; S [...] (466 aa)    
Predicted Functional Partners:
Chro_4457
PFAM: Nucleotidyl transferase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; COGs: COG0836 Mannose-1-phosphate guanylyltransferase; InterPro IPR005835; KEGG: npu:Npun_R5110 nucleotidyl transferase; PFAM: Nucleotidyl transferase; PRIAM: Mannose-1-phosphate guanylyltransferase; SPTR: Nucleotidyl transferase.
 
 
 0.945
Chro_3371
Nucleotidyl transferase; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Nucleotidyl transferase; Bacterial transferase hexapeptide (three repeats); Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I; COGs: COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon); InterPro IPR018357:IPR005835:IPR001451:IPR005844; KEGG: npu:Npun_R6155 nucleotidyl transferase [...]
  
 
 0.943
cugP
Nucleotidyl transferase; Catalyzes the formation of UDP-glucose, from UTP and glucose 1-phosphate.
  
 
 0.921
gmd
NAD-dependent epimerase/dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose.
  
 
 0.911
gmd-2
NAD-dependent epimerase/dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose.
  
 
 0.911
gmd-3
GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose.
  
 
 0.911
gmd-4
GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose.
  
 
 0.911
Chro_4739
PFAM: Mannitol dehydrogenase C-terminal domain; Mannitol dehydrogenase Rossmann domain; COGs: COG0246 Mannitol-1-phosphate/altronate dehydrogenase; InterPro IPR000669:IPR013131:IPR013118; KEGG: hoh:Hoch_4543 mannitol dehydrogenase domain protein; PFAM: Mannitol dehydrogenase domain; Mannitol dehydrogenase rossman domain; PRIAM: Mannitol 2-dehydrogenase; SPTR: Mannitol dehydrogenase rossman domain family.
     
 0.831
Chro_1659
PFAM: F5/8 type C domain; Cellulase (glycosyl hydrolase family 5); InterPro IPR000421:IPR001547; KEGG: ana:alr0290 hypothetical protein; PFAM: glycoside hydrolase family 5; coagulation factor 5/8 type domain protein; SPTR: S-layer associated multidomain endoglucanase.
    
  0.808
Chro_1904
PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; COGs: COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenase; InterPro IPR002328:IPR013154:IPR013149; KEGG: npu:Npun_R1726 alcohol dehydrogenase; PFAM: Alcohol dehydrogenase GroES domain protein; Alcohol dehydrogenase zinc-binding domain protein; SPTR: Alcohol dehydrogenase GroES domain protein.
  
 
  0.806
Your Current Organism:
Chroococcidiopsis thermalis
NCBI taxonomy Id: 251229
Other names: C. thermalis PCC 7203, Chroococcidiopsis sp. ATCC 27900, Chroococcidiopsis sp. PCC 7203, Chroococcidiopsis thermalis PCC 7203, Chroococcidiopsis thermalis str. PCC 7203
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