STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
fniIsopentenyl-diphosphate delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). (349 aa)    
Predicted Functional Partners:
ispH
4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
    
 0.920
Chro_1388
Farnesyl-diphosphate synthase; PFAM: Polyprenyl synthetase; COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: ava:Ava_2704 farnesyl-diphosphate synthase; PFAM: Polyprenyl synthetase; SPTR: Polyprenyl synthetase superfamily; Belongs to the FPP/GGPP synthase family.
  
 
 0.917
Chro_0574
Protein of unknown function UPF0047; PFAM: Uncharacterised protein family UPF0047; TIGRFAM: secondary thiamine-phosphate synthase enzyme; COGs: COG0432 conserved hypothetical protein; InterPro IPR001602; KEGG: npu:Npun_F0586 hypothetical protein; PFAM: protein of unknown function UPF0047; SPTR: Putative uncharacterized protein.
      0.621
Chro_0580
PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain; COGs: COG0277 FAD/FMN-containing dehydrogenase; InterProIPR017900:IPR000048:IPR016166:IPR006094:IPR 004113; KEGG: cyh:Cyan8802_0369 FAD linked oxidase domain protein; PFAM: FAD linked oxidase domain protein; SPTR: D-lactate dehydrogenase (Cytochrome).
  
 
 0.597
Chro_1602
Diguanylate cyclase; PFAM: HAMP domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain; COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR003660:IPR000160:IPR010916; KEGG: amr:AM1_5960 diguanylate cyclase; PFAM: GGDEF domain containing protein; histidine kinase HAMP region domain protein; SMART: GGDEF domain containing protein; histidine kinase HAMP region domain protein; SPTR: Diguanylate cyclase; TIGRFAM: diguanylate cyclase.
       0.570
Chro_1604
PFAM: Peptidase family S49; TIGRFAM: signal peptide peptidase SppA, 36K type; signal peptide peptidase SppA, 67K type; COGs: COG0616 Periplasmic serine protease (ClpP class); InterPro IPR004634:IPR002142:IPR004635; KEGG: npu:Npun_R1242 signal peptide peptidase SppA, 67K type; PFAM: peptidase S49; SPTR: Signal peptide peptidase SppA, 67K type; TIGRFAM: signal peptide peptidase SppA, 67K type; signal peptide peptidase SppA, 36K type.
       0.514
Chro_2092
PFAM: Aminotransferase class-V; COGs: COG0075 Serine-pyruvate aminotransferase/ aspartate aminotransferase; InterPro IPR020578:IPR004701:IPR000192; KEGG: npu:Npun_F4157 aminotransferase, class V; PFAM: aminotransferase class V; SPTR: Aminotransferase, class V.
  
 0.447
Chro_5229
PFAM: Proline dehydrogenase; Aldehyde dehydrogenase family; TIGRFAM: delta-1-pyrroline-5-carboxylate dehydrogenase, group 2, putative; delta-1-pyrroline-5-carboxylate dehydrogenase (PutA C-terminal domain); COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR002872:IPR015590:IPR016160:IPR005932; KEGG: npu:Npun_F5297 putative delta-1-pyrroline-5-carboxylate dehydrogenase; PFAM: Aldehyde Dehydrogenase; Proline dehydrogenase; SPTR: Putative delta-1-pyrroline-5-carboxylate dehydrogenase; TIGRFAM: delta-1-pyrroline-5-carboxylate dehydrogenase.
  
  
 0.430
Chro_4405
PFAM: Domain of unknown function; domain; Pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR017896:IPR017900:IPR002880:IPR019752:IPR 019456:IPR011766:IPR011895; KEGG: cyc:PCC7424_1261 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate [...]
     
 0.407
Chro_3699
FAD linked oxidase domain protein; PFAM: FAD binding domain; Cytokinin dehydrogenase 1, FAD and cytokinin binding; COGs: COG0277 FAD/FMN-containing dehydrogenase; InterPro IPR006094:IPR015345:IPR017909:IPR016166; KEGG: hau:Haur_4772 FAD linked oxidase domain-containing protein; PFAM: FAD linked oxidase domain protein; Cytokinin dehydrogenase 1 FAD and cytokinin binding; SPTR: FAD linked oxidase domain protein.
 
 
 0.404
Your Current Organism:
Chroococcidiopsis thermalis
NCBI taxonomy Id: 251229
Other names: C. thermalis PCC 7203, Chroococcidiopsis sp. ATCC 27900, Chroococcidiopsis sp. PCC 7203, Chroococcidiopsis thermalis PCC 7203, Chroococcidiopsis thermalis str. PCC 7203
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