Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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Chro_2016PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: glutathione-disulfide reductase, plant; COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterPro IPR013027:IPR000815:IPR012999:IPR004099; KEGG: npu:Npun_F0920 pyridine nucleotide-disulphide oxidoreductase dimerisation region; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SPTR: Pyridine nucleotide-disulphide oxidoreductase d [...] (449 aa)    
Predicted Functional Partners:
Chro_1978
Catalytic domain-containing protein of components of various dehydrogenase complexes; PFAM: 2-oxoacid dehydrogenases acyltransferase (catalytic domain); e3 binding domain; Biotin-requiring enzyme; TIGRFAM: pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form; COGs: COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) protein; InterProIPR003016:IPR000276:IPR000089:IPR004167:IPR 001078; KEGG: npu:Npun_F6414 branched-chain alpha-keto acid dehydrogenase subunit E2; PFAM: catalytic domain-containing protein of components of vari [...]
 0.985
Chro_2017
NADPH-glutathione reductase; Maintains high levels of reduced glutathione.
 
  
 
0.946
Chro_2423
PFAM: Glutaredoxin; Redoxin; TIGRFAM: Glutaredoxin-family domain; COGs: COG0678 Peroxiredoxin; InterProIPR011767:IPR014025:IPR017936:IPR011906:IPR 013740:IPR002109; KEGG: ava:Ava_4981 glutaredoxin-like region; PFAM: Redoxin domain protein; glutaredoxin; SPTR: Glutaredoxin-like region; TIGRFAM: glutaredoxin-family domain protein.
 
 0.944
gshB
PFAM: Prokaryotic glutathione synthetase, N-terminal domain; Prokaryotic glutathione synthetase, ATP-grasp domain; TIGRFAM: glutathione synthetase, prokaryotic; COGs: COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase); InterPro IPR011761:IPR004215:IPR004218:IPR006284; KEGG: ana:all3859 glutathione synthetase; PFAM: glutathione synthetase ATP-binding; glutathione synthetase domain protein; PRIAM: Glutathione synthase; SPTR: Glutathione synthetase; TIGRFAM: glutathione synthetase; Belongs to the prokaryotic GSH synthase family.
  
  
 0.943
Chro_1465
Transketolase central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 
 0.935
Chro_4110
PFAM: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain; COGs: COG0625 Glutathione S-transferase; InterPro IPR004045:IPR017933:IPR004046; KEGG: cyc:PCC7424_3947 glutathione S-transferase domain protein; PFAM: Glutathione S-transferase domain; SPTR: Glutathione S-transferase domain; Belongs to the GST superfamily.
  
 0.915
Chro_4001
PFAM: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain; COGs: COG0625 Glutathione S-transferase; InterPro IPR004045:IPR004046:IPR017933; KEGG: ava:Ava_3893 glutathione S-transferase-like protein; PFAM: Glutathione S-transferase domain; SPTR: Glutathione S-transferase-like; Belongs to the GST superfamily.
  
 0.913
Chro_4219
ChaC family protein; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.
  
  
  0.913
Chro_0852
PFAM: Glutathione S-transferase, N-terminal domain; Putative phosphatase (DUF442); Glutathione S-transferase, C-terminal domain; TIGRFAM: TIGR01244 family protein; COGs: COG0625 Glutathione S-transferase; InterProIPR004045:IPR017933:IPR005442:IPR004046:IPR 005939; KEGG: ava:Ava_5011 glutathione S-transferase-like protein; PFAM: Glutathione S-transferase domain; protein of unknown function DUF442; SPTR: Glutathione S-transferase-like.
   
 0.910
Chro_2891
Gamma-glutamyltransferase 1; PFAM: Gamma-glutamyltranspeptidase; TIGRFAM: gamma-glutamyltranspeptidase; COGs: COG0405 Gamma-glutamyltransferase; InterPro IPR000101; KEGG: bpt:Bpet0836 hypothetical protein; PFAM: gamma-glutamyltranspeptidase; PRIAM: Gamma-glutamyltransferase; SPTR: Gamma-glutamyltranspeptidase; TIGRFAM: gamma-glutamyltransferase.
     
 0.903
Your Current Organism:
Chroococcidiopsis thermalis
NCBI taxonomy Id: 251229
Other names: C. thermalis PCC 7203, Chroococcidiopsis sp. ATCC 27900, Chroococcidiopsis sp. PCC 7203, Chroococcidiopsis thermalis PCC 7203, Chroococcidiopsis thermalis str. PCC 7203
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