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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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co-expression
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[Homology]
Score
hisCPFAM: Aminotransferase class I and II; TIGRFAM: histidinol-phosphate aminotransferase; COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR005861:IPR004839; KEGG: ava:Ava_2242 histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; SPTR: Histidinol-phosphate aminotransferase 2; TIGRFAM: histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (381 aa)    
Predicted Functional Partners:
hisB
PFAM: Imidazoleglycerol-phosphate dehydratase; COGs: COG0131 Imidazoleglycerol-phosphate dehydratase; InterPro IPR000807:IPR020565; KEGG: npu:Npun_R5509 imidazoleglycerol-phosphate dehydratase; PFAM: imidazoleglycerol-phosphate dehydratase; PRIAM: Imidazoleglycerol-phosphate dehydratase; SPTR: Imidazoleglycerol-phosphate dehydratase.
 
 0.999
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
  
 0.995
hisI
PFAM: Phosphoribosyl-ATP pyrophosphohydrolase; Phosphoribosyl-AMP cyclohydrolase; TIGRFAM: phosphoribosyl-ATP pyrophosphohydrolase; COGs: COG0139 Phosphoribosyl-AMP cyclohydrolase; InterPro IPR002496:IPR021130:IPR008179; KEGG: npu:Npun_F4098 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; PFAM: phosphoribosyl-AMP cyclohydrolase; Phosphoribosyl-ATP pyrophosphohydrolase-like; SPTR: Phosphoribosyl-AMP cyclohydrolase; TIGRFAM: phosphoribosyl-ATP diphosphatase; In the N-terminal section; belongs to the PRA-CH family.
 
  
 0.986
Chro_0609
Arogenate dehydrogenase (NADP); PFAM: Prephenate dehydrogenase; COGs: COG0287 Prephenate dehydrogenase; InterPro IPR003099; KEGG: npu:Npun_R0978 arogenate dehydrogenase; PFAM: Prephenate dehydrogenase; SPTR: Prephenate dehydrogenase.
 
 
 0.962
Chro_3125
PFAM: Prephenate dehydrogenase; COGs: COG0287 Prephenate dehydrogenase; InterPro IPR004455:IPR003099; KEGG: ana:all0418 chorismate mutase/prephenate dehydrogenase; PFAM: Prephenate dehydrogenase; NADP oxidoreductase coenzyme F420-dependent; PRIAM: Chorismate mutase; SPTR: Chorismate mutase/prephenate dehydrogenase; manually curated.
  
 
 0.961
hisF
Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
 
  
 0.941
hisH
Imidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
 
  
 0.926
pheA
PFAM: Prephenate dehydratase; ACT domain; COGs: COG0077 Prephenate dehydratase; InterPro IPR001086:IPR018528:IPR002912; KEGG: npu:Npun_R3887 prephenate dehydratase; PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; PRIAM: Prephenate dehydratase; SPTR: Prephenate dehydratase domain protein.
  
 
 0.919
Chro_0712
PFAM: Phenylalanine and histidine ammonia-lyase; TIGRFAM: phenylalanine ammonia-lyase; COGs: COG2986 Histidine ammonia-lyase; InterPro IPR001106; KEGG: npu:Npun_R2068 phenylalanine/histidine ammonia-lyase; PFAM: phenylalanine/histidine ammonia-lyase; PRIAM: Histidine ammonia-lyase; SPTR: Phenylalanine/histidine ammonia-lyase.
  
 
 0.916
Chro_5233
PFAM: Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR001176:IPR004839:IPR004838; KEGG: npu:Npun_R0187 aspartate aminotransferase; PFAM: aminotransferase class I and II; SPTR: Aminotransferase, class I and II.
 
 
0.913
Your Current Organism:
Chroococcidiopsis thermalis
NCBI taxonomy Id: 251229
Other names: C. thermalis PCC 7203, Chroococcidiopsis sp. ATCC 27900, Chroococcidiopsis sp. PCC 7203, Chroococcidiopsis thermalis PCC 7203, Chroococcidiopsis thermalis str. PCC 7203
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