STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Chro_2397PFAM: 5-formyltetrahydrofolate cyclo-ligase family; TIGRFAM: 5,10-methenyltetrahydrofolate synthetase; COGs: COG0212 5-formyltetrahydrofolate cyclo-ligase; InterPro IPR002698; KEGG: npu:Npun_F3487 5-formyltetrahydrofolate cyclo-ligase; PFAM: 5-formyltetrahydrofolate cyclo-ligase; SPTR: 5-formyltetrahydrofolate cyclo-ligase; TIGRFAM: 5-formyltetrahydrofolate cyclo-ligase. (181 aa)    
Predicted Functional Partners:
folD
5,10-methylenetetrahydrofolate dehydrogenase (NADP+), methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
    
 0.933
purN
Formyltetrahydrofolate-dependent phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
  
 
 0.926
Chro_2700
Thiamine S protein; PFAM: ThiS family; TIGRFAM: molybdopterin converting factor, subunit 1, non-archaeal; COGs: COG1977 Molybdopterin converting factor small subunit; InterPro IPR003749; KEGG: npu:Npun_R6259 thiamineS protein; PFAM: thiamineS protein; SPTR: Putative uncharacterized protein.
      0.794
Chro_2398
PFAM: Bacterial regulatory proteins, tetR family; COGs: COG1309 Transcriptional regulator; InterPro IPR001647; KEGG: bbe:BBR47_27430 putative transcriptional regulator; PFAM: regulatory protein TetR; SPTR: Putative transcriptional regulator.
       0.773
Chro_2399
COGs: COG0596 hydrolase or acyltransferase (alpha/beta hydrolase superfamily); InterPro IPR000073; KEGG: bbe:BBR47_27420 putative hydrolase; PFAM: alpha/beta hydrolase fold; SPTR: Putative hydrolase.
       0.773
pheT
phenylalanyl-tRNA synthetase beta subunit; PFAM: tRNA synthetase B5 domain; B3/4 domain; Ferredoxin-fold anticodon binding domain; Putative tRNA binding domain; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit, non-spirochete bacterial; COGs: COG0072 Phenylalanyl-tRNA synthetase beta subunit; InterProIPR002547:IPR005121:IPR004532:IPR005146:IPR 005147; KEGG: npu:Npun_F1087 phenylalanyl-tRNA synthetase subunit beta; PFAM: B3/4 domain protein; t-RNA-binding domain-containing protein; tRNA synthetase B5; ferredoxin-fold anticodon-binding; PRIAM: Phenylalanine--tRNA ligase; SPTR: Phenyla [...]
 
  
 0.526
Chro_1606
PFAM: Rhomboid family; COGs: COG0705 membrane protein; InterPro IPR002610; KEGG: cyn:Cyan7425_0228 rhomboid family protein; PFAM: Rhomboid family protein; SPTR: Peptidase, S54 (Rhomboid) family.
  
    0.465
Chro_4260
PFAM: Rhomboid family; COGs: COG0705 membrane protein; InterPro IPR002610; KEGG: cyb:CYB_2002 S54 family peptidase; PFAM: Rhomboid family protein; SPTR: Peptidase, S54 (Rhomboid) family.
  
    0.465
Chro_4722
PFAM: Rhomboid family; COGs: COG0705 membrane protein; InterPro IPR002610; KEGG: npu:Npun_R0461 rhomboid family protein; PFAM: Rhomboid family protein; SPTR: Rhomboid family protein.
  
    0.465
Chro_4945
PFAM: Rhomboid family; COGs: COG0705 membrane protein; InterPro IPR002610; KEGG: npu:Npun_F6349 rhomboid family protein; PFAM: Rhomboid family protein; SPTR: Rhomboid-like protein.
  
    0.465
Your Current Organism:
Chroococcidiopsis thermalis
NCBI taxonomy Id: 251229
Other names: C. thermalis PCC 7203, Chroococcidiopsis sp. ATCC 27900, Chroococcidiopsis sp. PCC 7203, Chroococcidiopsis thermalis PCC 7203, Chroococcidiopsis thermalis str. PCC 7203
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