STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
Chro_2686Periplasmic sensor diguanylate cyclase/phosphodiesterase; PFAM: EAL domain; GGDEF domain; CHASE4 domain; PAS fold; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain; COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; InterProIPR000014:IPR000700:IPR001633:IPR000160:IPR 001610:IPR000215:IPR007892:IPR013767; KEGG: ppd:Ppro_2997 diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s); PFAM: EAL domain protein; GGDEF domain containing protein; CHASE4 domain protein; PAS fold domain protein; SMART: EAL domain protein; GG [...] (867 aa)    
Predicted Functional Partners:
Chro_4923
GAF sensor hybrid histidine kinase; PFAM: HAMP domain; Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467:IPR001789:IPR003660:IPR004358:IPR 003018:IPR003661:IPR003594:IPR018062; KEGG: cyn:Cyan7425_3768 GAF sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; histidine kinase HAMP region domain protein; response regulator receiver; SMART: ATP-binding region [...]
  
 
 0.990
Chro_4846
PFAM: Response regulator receiver domain; GAF domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR016132:IPR005467:IPR001789:IPR000014:IPR 000700:IPR004358:IPR013656:IPR003018:IPR013655:IPR003661:I PR003594:IPR001610; KEGG: npu:Npun_R4748 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS fold-4 domain protein; PAS fold-3 domain protein; respon [...]
 
 
 0.984
Chro_1980
Multi-component transcriptional regulator, winged helix family; PFAM: GGDEF domain; Response regulator receiver domain; Transcriptional regulatory protein, C terminal; Hpt domain; TIGRFAM: diguanylate cyclase (GGDEF) domain; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR000160:IPR001789:IPR008207:IPR001867; KEGG: amr:AM1_D0171 two-component transcriptional regulator/diguanylate cyclase (GGDEF); PFAM: GGDEF domain containing protein; response regulator receiver; transcriptional regulator domain-containing p [...]
  
 
0.976
Chro_5133
PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; Hpt domain; COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358:IPR003660:IPR003661:IPR003594:IPR 001789:IPR008207:IPR005467; KEGG: amr:AM1_5975 two-component hybrid sensor and regulator; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine [...]
 
 
 0.972
Chro_5472
PFAM: GAF domain; Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR003018:IPR000014:IPR001610:IPR003661:IPR 003594:IPR001789:IPR005467:IPR000700:IPR004358:IPR013767; KEGG: ana:alr1968 two-component hybrid sensor and regulator; PFAM: ATP-binding region ATPase domain protein; GAF domain protein; PAS fold domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region [...]
 
 
 0.964
Chro_1818
PAS/PAC sensor hybrid histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467:IPR001789:IPR000014:IPR000700:IPR 001610:IPR003661:IPR003594:IPR004358:IPR013656:IPR013767:I PR013655; KEGG: npu:Npun_R3572 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS fold-4 domain protein; PAS fo [...]
  
 
 0.958
Chro_4347
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); PFAM: EAL domain; HAMP domain; GGDEF domain; CHASE4 domain; PAS fold; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain; COGs: COG2200 FOG: EAL domain; InterProIPR000014:IPR000700:IPR001633:IPR003660:IPR 000160:IPR001610:IPR007892:IPR013656; KEGG: npu:Npun_F5467 diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s); PFAM: EAL domain protein; GGDEF domain containing protein; CHASE4 domain protein; histidine kinase HAMP region domain protein; PAS fold-4 domain protein; SMART: EAL domain protein; GGDE [...]
 
 
0.956
Chro_3264
Putative PAS/PAC sensor protein; PFAM: Response regulator receiver domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR001789:IPR013767:IPR000014; KEGG: npu:Npun_R5896 response regulator receiver modulated PAS/PAC sensor protein; PFAM: response regulator receiver; PAS fold domain protein; SMART: response regulator receiver; PAS domain containing protein; SPTR: Response regulator receiver modulated PAS/PAC sensor protein; TIGRFAM: PAS sensor protein.
 
 
0.955
Chro_4774
Diguanylate cyclase with PAS/PAC and GAF sensors; PFAM: GAF domain; GGDEF domain; CHASE3 domain; PAS fold; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain; COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterProIPR000014:IPR000700:IPR000160:IPR003018:IPR 007891:IPR013767:IPR013656:IPR001610; KEGG: npu:Npun_R1685 multi-sensor hybrid histidine kinase; PFAM: GGDEF domain containing protein; GAF domain protein; CHASE3 domain protein; PAS fold domain protein; PAS fold-4 domain protein; SMART: GGDEF domain containing protein; PAS dom [...]
 
 
0.954
Chro_1625
Response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); PFAM: EAL domain; GGDEF domain; Response regulator receiver domain; PAS fold; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain; COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; InterProIPR001789:IPR000014:IPR000700:IPR001633:IPR 000160:IPR001610:IPR013655; KEGG: amr:AM1_0016 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor; PFAM: EAL domain protein; GGDEF domain containing protein; response regulator receiver; PAS fol [...]
 
 
0.953
Your Current Organism:
Chroococcidiopsis thermalis
NCBI taxonomy Id: 251229
Other names: C. thermalis PCC 7203, Chroococcidiopsis sp. ATCC 27900, Chroococcidiopsis sp. PCC 7203, Chroococcidiopsis thermalis PCC 7203, Chroococcidiopsis thermalis str. PCC 7203
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