STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
ppkPolyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. (723 aa)    
Predicted Functional Partners:
Chro_1932
Protein of unknown function DUF344; PFAM: Polyphosphate kinase 2 (PPK2); TIGRFAM: polyphosphate kinase 2, PA0141 family; COGs: COG2326 conserved hypothetical protein; InterPro IPR016898:IPR005660; KEGG: cyn:Cyan7425_4669 protein of unknown function DUF344; PFAM: protein of unknown function DUF344; SPTR: Putative uncharacterized protein.
 
  
 0.956
Chro_1664
PFAM: HD domain; Ppx/GppA phosphatase family; TIGRFAM: exopolyphosphatase; COGs: COG0248 Exopolyphosphatase; InterPro IPR003695:IPR006674; KEGG: ava:Ava_3530 Ppx/GppA phosphatase; PFAM: Ppx/GppA phosphatase; metal-dependent phosphohydrolase HD sub domain; PRIAM: Guanosine-5'-triphosphate,3'-diphosphate diphosphatase; SPTR: Ppx/GppA phosphatase.
  
 0.954
ppa
Inorganic diphosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
     
 0.924
Chro_2356
Protein of unknown function DUF344; PFAM: Polyphosphate kinase 2 (PPK2); TIGRFAM: polyphosphate:nucleotide phosphotransferase, PPK2 family; COGs: COG2326 conserved hypothetical protein; InterPro IPR016898:IPR005660; KEGG: met:M446_5330 hypothetical protein; PFAM: protein of unknown function DUF344; SPTR: Putative uncharacterized protein.
 
   
 0.800
Chro_2740
KEGG: ava:Ava_0962 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.674
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.608
Chro_2738
PFAM: Response regulator receiver domain; COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR001789; KEGG: npu:Npun_F5759 response regulator receiver protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver protein.
       0.428
Chro_3205
PFAM: Pyruvate kinase, barrel domain; PEP-utilising enzyme, mobile domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; COGs: COG0469 Pyruvate kinase; InterProIPR018209:IPR015793:IPR015794:IPR008279:IPR 001697; KEGG: ava:Ava_1694 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PEP-utilising protein mobile region; SPTR: Pyruvate kinase; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family.
     
 0.413
purM
Phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: phosphoribosylaminoimidazole synthetase; COGs: COG0150 Phosphoribosylaminoimidazole (AIR) synthetase; InterPro IPR004733:IPR000728:IPR010918; KEGG: naz:Aazo_3150 phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein domain protein; AIR synthase related protein; PRIAM: Phosphoribosylformylglycinamidine cyclo-ligase; SPTR: Phosphoribosylformylglycinamidine cyclo-ligase; TIGRFAM: phosphoribosylformylgl [...]
    
 0.412
Your Current Organism:
Chroococcidiopsis thermalis
NCBI taxonomy Id: 251229
Other names: C. thermalis PCC 7203, Chroococcidiopsis sp. ATCC 27900, Chroococcidiopsis sp. PCC 7203, Chroococcidiopsis thermalis PCC 7203, Chroococcidiopsis thermalis str. PCC 7203
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