STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
coaXPutative transcriptional acitvator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (268 aa)    
Predicted Functional Partners:
panC/cmk
Pantothenate synthetase, cytidylate kinase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the N-terminal section; belongs to the pantothenate synthetase family.
 
 
 0.976
coaD
Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
 
  
 0.941
Chro_2985
Phosphopantothenoylcysteine decarboxylase, Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.
  
 
 0.931
Chro_1292
PFAM: Protein of unknown function, DUF479; COGs: COG3124 conserved hypothetical protein; InterPro IPR007431; KEGG: cyc:PCC7424_1921 protein of unknown function DUF479; PFAM: protein of unknown function DUF479; SPTR: Putative uncharacterized protein.
     
  0.900
panD
L-aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
  
  
 0.745
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
   
   0.721
Chro_2763
PFAM: Metallo-beta-lactamase superfamily; Flavin reductase like domain; COGs: COG0426 flavoprotein; InterPro IPR008254:IPR002563; KEGG: ava:Ava_1802 flavin reductase-like, FMN-binding; PFAM: flavin reductase domain protein FMN-binding; SPTR: Flavin reductase-like, FMN-binding.
       0.587
Chro_2765
PFAM: Ribbon-helix-helix protein, copG family; KEGG: naz:Aazo_2645 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.584
Chro_2766
Transcriptional modulator of MazE/toxin, MazF; Toxic component of a type II toxin-antitoxin (TA) system.
       0.584
Chro_2767
PfkB domain protein; PFAM: pfkB family carbohydrate kinase; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611; KEGG: ana:alr4681 hypothetical protein; PFAM: PfkB domain protein; SPTR: PfkB.
       0.530
Your Current Organism:
Chroococcidiopsis thermalis
NCBI taxonomy Id: 251229
Other names: C. thermalis PCC 7203, Chroococcidiopsis sp. ATCC 27900, Chroococcidiopsis sp. PCC 7203, Chroococcidiopsis thermalis PCC 7203, Chroococcidiopsis thermalis str. PCC 7203
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