STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Chro_2771Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase; COGs: COG4221 Short-chain alcohol dehydrogenase of unknown specificity; InterPro IPR002347:IPR002198; KEGG: ava:Ava_2888 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase SDR; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (257 aa)    
Predicted Functional Partners:
Chro_3730
Amino acid adenylation domain protein; PFAM: Male sterility protein; Phosphopantetheine attachment site; Condensation domain; AMP-binding enzyme; TIGRFAM: amino acid adenylation domain; thioester reductase domain; COGs: COG1020 Non-ribosomal peptide synthetase modules and related protein; InterProIPR020459:IPR006162:IPR020845:IPR001242:IPR 000873:IPR006163:IPR013120:IPR009081:IPR010071:IPR010080; KEGG: cyc:PCC7424_5750 amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; phosphopantetheine-binding; Male sterility domain; SPTR: A [...]
 
  
 0.913
kbl
2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
     
  0.900
Chro_5343
8-amino-7-oxononanoate synthase; PFAM: Aminotransferase class I and II; COGs: COG0156 7-keto-8-aminopelargonate synthetase; InterPro IPR004839; KEGG: cyc:PCC7424_2980 aminotransferase class I and II; PFAM: aminotransferase class I and II; PRIAM: 8-amino-7-oxononanoate synthase; SPTR: Aminotransferase, classes I and II superfamily.
     
  0.900
Chro_3658
Amino acid adenylation domain protein; PFAM: Phosphopantetheine attachment site; Nonribosomal peptide synthase; AMP-binding enzyme; Condensation domain; TIGRFAM: amino acid adenylation domain; COGs: COG1020 Non-ribosomal peptide synthetase modules and related protein; InterProIPR010916:IPR020845:IPR010071:IPR001242:IPR 013624:IPR000873:IPR006163:IPR009081; KEGG: amr:AM1_A0227 barbamide biosynthesis protein BarG; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; Non-ribosomal peptide synthetase; phosphopantetheine-binding; SPTR: Barbamide biosynthesis protein BarG; [...]
 
      0.857
Chro_2580
Amino acid adenylation domain protein; PFAM: Phosphopantetheine attachment site; AMP-binding enzyme; Condensation domain; TIGRFAM: amino acid adenylation domain; COGs: COG1020 Non-ribosomal peptide synthetase modules and related protein; InterProIPR009081:IPR010071:IPR006162:IPR020845:IPR 001242:IPR000873:IPR006163; KEGG: npu:Npun_R3025 amino acid adenylation domain-containing protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; phosphopantetheine-binding; SPTR: Amino acid adenylation domain protein; TIGRFAM: amino acid adenylation domain protein.
 
  
 0.825
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
 
      0.774
Chro_2126
Amino acid adenylation domain protein; PFAM: Thioesterase domain; Phosphopantetheine attachment site; Condensation domain; AMP-binding enzyme; COGs: COG1020 Non-ribosomal peptide synthetase modules and related protein; InterProIPR010071:IPR020845:IPR009081:IPR001242:IPR 000873:IPR006163:IPR001031; KEGG: npu:Npun_CR072 amino acid adenylation domain-containing protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; phosphopantetheine-binding; Thioesterase; SPTR: Amino acid adenylation domain protein; TIGRFAM: amino acid adenylation domain protein.
 
  
 0.671
Chro_0078
Amino acid adenylation domain protein; PFAM: Phosphopantetheine attachment site; Thioesterase domain; AMP-binding enzyme; Condensation domain; TIGRFAM: amino acid adenylation domain; COGs: COG1020 Non-ribosomal peptide synthetase modules and related protein; InterProIPR001242:IPR000873:IPR006163:IPR001031:IPR 020845:IPR009081:IPR010071; KEGG: npu:Npun_R3023 amino acid adenylation domain-containing protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; phosphopantetheine-binding; Thioesterase; SPTR: Amino acid adenylation domain protein; TIGRFAM: amino acid ade [...]
 
  
 0.665
Chro_2576
PFAM: Thioesterase domain; Phosphopantetheine attachment site; AMP-binding enzyme; COGs: COG3319 Thioesterase domains of type I polyketide synthase or non-ribosomal peptide synthetase; InterProIPR009081:IPR006162:IPR000873:IPR006163:IPR 001031; KEGG: npu:Npun_F3173 amino acid adenylation domain-containing protein; PFAM: Thioesterase; AMP-dependent synthetase and ligase; phosphopantetheine-binding; SPTR: Peptide synthetase.
 
  
 0.645
Chro_1884
Amino acid adenylation domain protein; PFAM: Male sterility protein; Phosphopantetheine attachment site; Methyltransferase domain; AMP-binding enzyme; TIGRFAM: amino acid adenylation domain; thioester reductase domain; COGs: COG1020 Non-ribosomal peptide synthetase modules and related protein; InterProIPR010071:IPR010080:IPR006162:IPR009081:IPR 000873:IPR013217:IPR006163:IPR013120; KEGG: npu:Npun_F2462 amino acid adenylation domain-containing protein; PFAM: AMP-dependent synthetase and ligase; Methyltransferase type 12; phosphopantetheine-binding; Male sterility domain; SPTR: Putative [...]
  
   0.597
Your Current Organism:
Chroococcidiopsis thermalis
NCBI taxonomy Id: 251229
Other names: C. thermalis PCC 7203, Chroococcidiopsis sp. ATCC 27900, Chroococcidiopsis sp. PCC 7203, Chroococcidiopsis thermalis PCC 7203, Chroococcidiopsis thermalis str. PCC 7203
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