STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Chro_2912acetyl-CoA acetyltransferase; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases; COGs: COG0183 Acetyl-CoA acetyltransferase; InterProIPR020616:IPR020617:IPR020615:IPR020610:IPR 020613:IPR002155; KEGG: cyn:Cyan7425_3064 acetyl-CoA acetyltransferase; PFAM: Thiolase-like; SPTR: Acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa)    
Predicted Functional Partners:
Chro_2913
PFAM: Enoyl-CoA hydratase/isomerase family; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; COGs: COG1250 3-hydroxyacyl-CoA dehydrogenase; InterPro IPR006176:IPR006108:IPR001753:IPR000463; KEGG: cyn:Cyan7425_3065 3-hydroxyacyl-CoA dehydrogenase NAD-binding; PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase domain-containing protein; Enoyl-CoA hydratase/isomerase; SPTR: 3-hydroxyacyl-CoA dehydrogenase NAD-binding.
 0.999
Chro_2911
Protein of unknown function DUF1974; PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, middle domain; Domain of unknown function (DUF1974); Acyl-CoA dehydrogenase, N-terminal domain; COGs: COG1960 Acyl-CoA dehydrogenase; InterProIPR006092:IPR006091:IPR006090:IPR015396:IPR 006089; KEGG: cyn:Cyan7425_3063 acyl-CoA dehydrogenase; PFAM: protein of unknown function DUF1974; acyl-CoA dehydrogenase domain-containing protein; SPTR: Putative uncharacterized protein.
 
 0.995
Chro_2715
PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, N-terminal domain; COGs: COG1960 Acyl-CoA dehydrogenase; InterPro IPR006092; KEGG: tkm:TK90_0970 acyl-CoA dehydrogenase domain protein; PFAM: acyl-CoA dehydrogenase domain-containing protein; SPTR: Acyl-CoA dehydrogenase domain protein.
 
 0.933
Chro_3309
AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme; COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR020845:IPR000873; KEGG: sbi:SORBI_02g023690 hypothetical protein; PFAM: AMP-dependent synthetase and ligase; SPTR: AMP-dependent synthetase and ligase.
 
 
 0.918
Chro_5515
Methylmalonate-semialdehyde dehydrogenase (acylating); PFAM: Aldehyde dehydrogenase family; TIGRFAM: methylmalonic acid semialdehyde dehydrogenase; COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR016160:IPR010061:IPR015590; KEGG: dfe:Dfer_5699 methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; SPTR: Methylmalonate-semialdehyde dehydrogenase; TIGRFAM: methylmalonate-semialdehyde dehydrogenase.
   
 0.917
Chro_4405
PFAM: Domain of unknown function; domain; Pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR017896:IPR017900:IPR002880:IPR019752:IPR 019456:IPR011766:IPR011895; KEGG: cyc:PCC7424_1261 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate [...]
  
 
 0.913
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.906
Chro_1071
PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, N-terminal domain; COGs: COG1960 Acyl-CoA dehydrogenase; InterPro IPR006092:IPR013107; KEGG: gvi:glr3048 hypothetical protein; PFAM: acyl-CoA dehydrogenase domain-containing protein; Acyl-CoA dehydrogenase type 2 domain; SPTR: Glr3048 protein.
 
 0.900
Chro_2254
PFAM: Citrate synthase; TIGRFAM: 2-methylcitrate synthase/citrate synthase II; COGs: COG0372 Citrate synthase; InterPro IPR019810:IPR002020:IPR011278; KEGG: npu:Npun_R5627 citrate synthase; PFAM: Citrate synthase; PRIAM: Citrate (Si)-synthase; SPTR: Citrate synthase; TIGRFAM: 2-methylcitrate synthase/citrate synthase II; Belongs to the citrate synthase family.
  
 0.900
Chro_2603
PFAM: CoA binding domain; CoA-ligase; TIGRFAM: succinyl-CoA synthetase, alpha subunit; COGs: COG0074 Succinyl-CoA synthetase alpha subunit; InterPro IPR005810:IPR003781:IPR005811; KEGG: npu:Npun_F5184 CoA-binding domain-containing protein; PFAM: CoA-binding domain protein; ATP-citrate lyase/succinyl-CoA ligase; SPTR: CoA-binding.
  
 0.875
Your Current Organism:
Chroococcidiopsis thermalis
NCBI taxonomy Id: 251229
Other names: C. thermalis PCC 7203, Chroococcidiopsis sp. ATCC 27900, Chroococcidiopsis sp. PCC 7203, Chroococcidiopsis thermalis PCC 7203, Chroococcidiopsis thermalis str. PCC 7203
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.